Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States.
Department of Medicine, University of California, San Francisco, California, United States.
Community Health Equity Res Policy. 2023 Jan;43(2):133-141. doi: 10.1177/0272684X211006590. Epub 2021 Apr 4.
We assessed built environment (residential density, landuse mix and aesthetics) and HIV linkage to care (LTC) among 1,681 (18-49 years-old) residents of 15 Mpumalanga villages, South Africa.
Multilevel models (linear-binomial) were used for the association between built environment, measured using NEWS for Africa, and LTC from a clinical database of 9 facilities (2015-2018). Additionally, we assessed effect-measure modification by universal test-and-treat policy (UTT).
We observed, a significant association in the adjusted 3-month probability of LTC for residential density (risk difference (RD)%: 5.6, 95%CI: 1.2-10.1), however, no association for land-use mix (RD%: 2.4, 95%CI: -0.4, 5.2) and aesthetics (RD%: -1.2, 95%CI: -4.5-2.2). Among those diagnosed after UTT, residents of high land-use villages were more likely to link-to-care than those of low land-use villages at 12 months (RD%: 4.6, 95%CI: 1.1-8.1, p < 0.04), however, not at 3 months (RD%: 3.0, 95%CI: -2.1-8.0, p > 0.10).
Findings suggest, better built environment conditions (adequate infrastructure, proximity to services etc.) help facilitate LTC. Moreover, UTT appears to have a protective effect on LTC.
我们评估了南非 15 个姆普马兰加村庄的 1681 名(18-49 岁)居民的建筑环境(居住密度、土地使用混合和美观)和艾滋病毒与护理的关联(LTC)。
使用非洲新闻环境评估量表(NEWS for Africa)测量的建筑环境与 9 个设施的临床数据库中从 HIV 确诊到接受护理(LTC)的时间(2015-2018 年)之间的关联,采用多水平模型(线性-二项式)进行分析。此外,我们还评估了普遍检测和治疗政策(UTT)的效应修饰作用。
我们观察到,在调整后的 3 个月 LTC 概率中,居住密度与 LTC 呈显著正相关(风险差异(RD)%:5.6,95%CI:1.2-10.1),然而,土地使用混合(RD%:2.4,95%CI:-0.4,5.2)和美观(RD%:-1.2,95%CI:-4.5-2.2)与 LTC 无显著关联。在 UTT 后被诊断出 HIV 的人群中,与低土地使用村庄的居民相比,高土地使用村庄的居民在 12 个月时更有可能接受 LTC(RD%:4.6,95%CI:1.1-8.1,p<0.04),但在 3 个月时没有差异(RD%:3.0,95%CI:-2.1-8.0,p>0.10)。
研究结果表明,更好的建筑环境条件(充足的基础设施、接近服务等)有助于促进 LTC。此外,UTT 似乎对 LTC 具有保护作用。