高强度间歇训练对超重或肥胖成年人肝内脂肪含量的影响：荟萃分析。
The impact of high intensity interval training on liver fat content in overweight or obese adults: A meta-analysis.
机构信息
Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran.
The Early Life Research Unit, Academic Division of Child Health and Nottingham Digestive Disease Centre and Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham, NG7 2UH, United Kingdom.
出版信息
Physiol Behav. 2021 Jul 1;236:113416. doi: 10.1016/j.physbeh.2021.113416. Epub 2021 Apr 3.
Liver fat is a marker of the metabolic derangements associated with obesity for which exercise training is a potential therapy. We therefore performed a systematic meta-analysis to investigate the effect of high intensity interval training (HIIT) on liver fat content in overweight or obese adults with metabolic disorders. PubMed, Scopus, Web of Science and the Cochrane were searched up to October 2020 for HIIT vs. Control (CON) or HIIT vs. moderate intensity interval training (MICT) studies on liver fat content in overweight and obese individuals with metabolic disorders. Standardized mean differences (SMD) and 95% confidence intervals (95% CIs) were calculated. Ten studies involving 333 participants were included in the meta-analysis. Based on studies that directly compared HIIT and CON (6 studies), HIIT was beneficial for promoting a reduction in liver fat [-0.51 (95% CI: -0.85 to -0.17), p = 0.003]. However, there were no significant evidence for an effect of HIIT on liver fat [-0.07 (95% CI: -0.33 to 0.19), p = 0.59], when compared with MICT (7 studies). These results suggest that a HIIT could induce improvements in liver fat of overweight and obese adults with metabolic disorders despite no weight loss.
肝脏脂肪是与肥胖相关的代谢紊乱的标志物，而运动训练是一种潜在的治疗方法。因此，我们进行了系统的荟萃分析，以调查高强度间歇训练（HIIT）对代谢紊乱的超重或肥胖成年人肝脏脂肪含量的影响。截至 2020 年 10 月，我们在 PubMed、Scopus、Web of Science 和 Cochrane 中搜索了 HIIT 与对照（CON）或 HIIT 与中等强度间歇训练（MICT）比较超重和肥胖代谢紊乱个体肝脏脂肪含量的研究。计算了标准化均数差（SMD）和 95%置信区间（95%CI）。荟萃分析纳入了 10 项涉及 333 名参与者的研究。基于直接比较 HIIT 和 CON 的研究（6 项研究），HIIT 有利于促进肝脏脂肪减少[-0.51（95%CI：-0.85 至-0.17），p=0.003]。然而，与 MICT（7 项研究）相比，HIIT 对肝脏脂肪的影响没有显著证据[-0.07（95%CI：-0.33 至 0.19），p=0.59]。这些结果表明，尽管没有体重减轻，HIIT 可以改善代谢紊乱的超重和肥胖成年人的肝脏脂肪。
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