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髌股关节炎行现代髌股关节置换术与全膝关节置换术的中期结果比较:系统评价和荟萃分析。

Midterm results of modern patellofemoral arthroplasty versus total knee arthroplasty for isolated patellofemoral arthritis: systematic review and meta-analysis of comparative studies.

机构信息

Department of Trauma and Orthopaedic Surgery, Cork University Hospital, Wilton, Cork, Ireland.

出版信息

Arch Orthop Trauma Surg. 2022 May;142(5):851-859. doi: 10.1007/s00402-021-03882-4. Epub 2021 Apr 7.

Abstract

BACKGROUND

Both Patellofemoral Arthroplasty (PFA) and Total Knee Arthroplasty (TKA) are accepted surgical options for end-stage isolated patellofemoral osteoarthritis (PFOA). We performed a systematic review and meta-analysis to compare outcomes of PFA and TKA by evaluation of the patient-reported outcome measures (PROMs).

METHODS

We systematically identified publications reporting on patients that underwent either TKA or modern PFA for isolated PFOA. Meta-analysis software was used to screen for potential articles with at least two years' follow-up. Data were extracted and analysed for all PROMs operating time, postoperative inpatient time, complications and cost. We included five studies in our cumulative meta-analysis and reviewed them using Review Manager V.5.0. We computed the risk ratio as a measure of the treatment effect, taking into account heterogeneity. We used random-effect models.

RESULTS

No significant difference was found between both TKA and PFA in the context of operating time. No significant difference after five years' follow-up was found between the two treatment options in terms of UCLA score and patient satisfaction. PFA showed significant improvement in WOMAC score at five-year follow-up, less postoperative inpatient time, better cost-effectiveness and significantly less blood loss.

CONCLUSION

PFA seems to be a viable alternative to TKA for treatment of isolated PFOA in appropriately selected patients. PFA showed less postoperative inpatient time and blood loss with similar PROMs to the TKA. Moreover, it is an economically beneficial joint-preserving procedure.

摘要

背景

髌股关节成形术(PFA)和全膝关节成形术(TKA)都是治疗终末期孤立性髌股关节炎(PFOA)的可接受的手术选择。我们进行了系统评价和荟萃分析,通过评估患者报告的结果测量(PROMs)来比较 PFA 和 TKA 的结果。

方法

我们系统地确定了报告接受 TKA 或现代 PFA 治疗孤立性 PFOA 的患者的出版物。使用荟萃分析软件筛选至少有两年随访的潜在文章。提取并分析了所有 PROM 操作时间、术后住院时间、并发症和成本的数据。我们在累积荟萃分析中纳入了五项研究,并使用 Review Manager V.5.0 对其进行了审查。我们计算了风险比作为治疗效果的衡量标准,同时考虑了异质性。我们使用随机效应模型。

结果

在手术时间方面,TKA 和 PFA 之间没有发现显著差异。在五年随访时,两种治疗方案在 UCLA 评分和患者满意度方面没有发现显著差异。PFA 在五年随访时在 WOMAC 评分方面表现出显著改善,术后住院时间较短,成本效益更好,失血量明显减少。

结论

PFA 似乎是治疗适当选择的孤立性 PFOA 的 TKA 的可行替代方案。PFA 术后住院时间和失血量较少,与 TKA 的 PROM 相似。此外,它是一种具有经济效益的关节保留手术。

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