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CST（卡斯特atin）的心肌保护作用机制与巨噬细胞的免疫抑制有关。

Immunosuppression of Macrophages Underlies the Cardioprotective Effects of CST (Catestatin).

机构信息

Department of Medicine (W.Y., E.A., M.A.L., H.G., J.Z., S.M., G.B., F.S., N.J.G.W., P.G., S.K.M.), University of California San Diego, La Jolla.

VA San Diego Healthcare System, CA (T.P., K.T., J.M.S., D.M.R., N.J.G.W., H.H.P., S.K.M.).

出版信息

Hypertension. 2021 May 5;77(5):1670-1682. doi: 10.1161/HYPERTENSIONAHA.120.16809. Epub 2021 Apr 7.

DOI:10.1161/HYPERTENSIONAHA.120.16809
PMID:33826401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8116433/
Abstract

[Figure: see text].

摘要

[图：见正文]。

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Molecular Imaging Visualizes Recruitment of Inflammatory Monocytes and Macrophages to the Injured Heart.分子成像可观察到炎症性单核细胞和巨噬细胞向受损心脏的募集。
Circ Res. 2019 Mar 15;124(6):881-890. doi: 10.1161/CIRCRESAHA.118.314030.
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Catestatin as a Target for Treatment of Inflammatory Diseases.
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J Endocr Soc. 2025 May 15;9(7):bvaf090. doi: 10.1210/jendso/bvaf090. eCollection 2025 Jul.
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Chromogranin A deficiency attenuates tauopathy by altering epinephrine-alpha-adrenergic receptor signaling in PS19 mice.嗜铬粒蛋白A缺乏通过改变PS19小鼠中的肾上腺素-α-肾上腺素能受体信号传导来减轻tau蛋白病。
Nat Commun. 2025 May 20;16(1):4703. doi: 10.1038/s41467-025-59682-6.
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A complex role of chromogranin A and its peptides in inflammation, autoimmunity, and infections.嗜铬粒蛋白A及其肽在炎症、自身免疫和感染中的复杂作用。
Front Immunol. 2025 Apr 30;16:1567874. doi: 10.3389/fimmu.2025.1567874. eCollection 2025.
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Catestatin in Cardiovascular Diseases.心血管疾病中的降钙素抑制肽
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The physiological anti-hypertensive peptide catestatin and its common human variant Gly364Ser: differential cardiovascular effects in a rat model of hypertension.生理性抗高血压肽降钙素抑制肽及其常见人类变体Gly364Ser：在高血压大鼠模型中的不同心血管效应。
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J Exp Med. 2018 Jan 2;215(1):21-33. doi: 10.1084/jem.20171773. Epub 2017 Dec 15.
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Inflammation, Immunity, and Hypertension.炎症、免疫与高血压
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The Contribution of Inflammation to the Development of Hypertension Mediated by Increased Arterial Stiffness.炎症对动脉僵硬度增加介导的高血压发展的作用。
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