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酵母核糖体蛋白L2与大鼠肝脏核糖体蛋白L4和L24之间的免疫同源性。

Immunological homologies between yeast ribosomal protein L2 and rat liver ribosomal proteins L4 and L24.

作者信息

Kreutzfeldt C, Potthast M

机构信息

Institut für Pharmakologie und Toxikologie, Philipps-Universität Marburg, Federal Republic of Germany.

出版信息

Curr Genet. 1988 Mar;13(3):235-9. doi: 10.1007/BF00387769.

Abstract

Polyclonal antibodies raised against ribosomal protein (r-protein) L2 of Schizosaccharomyces pombe were used to check for cross-reactions with total r-proteins of rat liver. Using this procedure, the rat liver r-proteins, L4 and L24, were identified as being immunologically related to yeast L2. In additional, homologies between rat liver L4 and L24 were detected. The possible implications for the regulation of r-protein synthesis are discussed.

摘要

用针对粟酒裂殖酵母核糖体蛋白(r蛋白)L2产生的多克隆抗体来检测与大鼠肝脏总r蛋白的交叉反应。通过这个程序,大鼠肝脏r蛋白L4和L24被鉴定为与酵母L2有免疫相关性。此外,还检测到大鼠肝脏L4和L24之间的同源性。文中讨论了r蛋白合成调控的可能影响。

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