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一种新型免提超声贴片,用于连续监测颈动脉的定量多普勒。

A novel, hands-free ultrasound patch for continuous monitoring of quantitative Doppler in the carotid artery.

机构信息

Health Sciences North Research Institute and the Northern Ontario School of Medicine, Sudbury, ON, Canada.

Flosonics Medical, Sudbury, ON, Canada.

出版信息

Sci Rep. 2021 Apr 8;11(1):7780. doi: 10.1038/s41598-021-87116-y.

Abstract

Quantitative Doppler ultrasound of the carotid artery has been proposed as an instantaneous surrogate for monitoring rapid changes in left ventricular output. Tracking immediate changes in the arterial Doppler spectrogram has value in acute care settings such as the emergency department, operating room and critical care units. We report a novel, hands-free, continuous-wave Doppler ultrasound patch that adheres to the neck and tracks Doppler blood flow metrics in the common carotid artery using an automated algorithm. String and blood-mimicking test objects demonstrated that changes in velocity were accurately measured using both manually and automatically traced Doppler velocity waveforms. In a small usability study with 22 volunteer users (17 clinical, 5 lay), all users were able to locate the carotid Doppler signal on a volunteer subject, and, in a subsequent survey, agreed that the device was easy to use. To illustrate potential clinical applications of the device, the Doppler ultrasound patch was used on a healthy volunteer undergoing a passive leg raise (PLR) as well as on a congestive heart failure patient at resting baseline. The wearable carotid Doppler patch holds promise because of its ease-of-use, velocity measurement accuracy, and ability to continuously record Doppler spectrograms over many cardiac and respiratory cycles.

摘要

颈总动脉定量多普勒超声已被提议作为监测左心室输出快速变化的即时替代指标。在急诊室、手术室和重症监护病房等急性护理环境中,跟踪动脉多普勒频谱图的即时变化具有价值。我们报告了一种新颖的、无需手持的连续波多普勒超声贴片,它可以贴合在颈部,并使用自动算法跟踪颈总动脉的多普勒血流参数。线和血液模拟测试对象表明,使用手动和自动跟踪的多普勒速度波形可以准确测量速度变化。在一项有 22 名志愿者(17 名临床医生,5 名非临床医生)参与的小型可用性研究中,所有志愿者都能够在志愿者身上定位颈总动脉多普勒信号,并且在随后的调查中,他们都认为该设备易于使用。为了说明该设备的潜在临床应用,我们在一名健康志愿者进行被动抬腿(PLR)期间以及一名充血性心力衰竭患者静息基线期间使用了该可穿戴颈动脉多普勒贴片。由于其易于使用、速度测量准确性以及能够在多个心脏和呼吸周期内连续记录多普勒频谱图,这种可穿戴颈动脉多普勒贴片具有广阔的应用前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2749/8032670/4f1ac8787d3c/41598_2021_87116_Fig1_HTML.jpg

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