Center for Drug and Alcohol Research and Collaborating Center on Alcohol and Drugs, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Center for Drug and Alcohol Research and Collaborating Center on Alcohol and Drugs, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Psychiatry Res. 2021 Jun;300:113915. doi: 10.1016/j.psychres.2021.113915. Epub 2021 Mar 31.
The COVID-19 pandemic is a public health emergency. Individuals with substance use disorder have a higher risk of infection and may suffer from more severe forms of the disease. Our goal is to investigate the prevalence of risk factors for COVID-19 severity in individuals with different substance use and explore whether specific types of substance are potentially associated with more clinical risk factors which could increase morbimortality in this population. The sample included 821 men hospitalized at an inpatient Addiction unit (305 alcohol users, 233 cocaine/crack users, and 283 multiusers). Data were collected using the Addiction Severity Index version 6. The most prevalent risk factors for COVID-19 severity observed in our sample were: smoking (82.5%), arterial hypertension (26.6%), respiratory problems (23.4%), and history of homelessness (25.1%). Arterial hypertension and cirrhosis occurred more frequently among alcohol users. Multiusers lived in the streets longer and had a higher prevalence of HIV than alcohol users. Overall, 28% of the sample had three or more risk factors. The frequency of risk factors was high and this scenario suggests that these individuals could be more susceptible to worse COVID-19 prognosis. Therefore, prevention strategies directed at specific characteristics of substance users merit attention during the pandemic.
译文：新型冠状病毒肺炎疫情是一场公共卫生紧急事件。患有物质使用障碍的个体感染的风险更高，并且可能患有更严重的疾病。我们的目标是调查不同物质使用个体中 COVID-19 严重程度的危险因素的流行情况，并探讨特定类型的物质是否与更多的临床危险因素有关，这些危险因素可能会增加该人群的病死率。该样本包括 821 名在住院成瘾病房住院的男性（305 名酒精使用者、233 名可卡因/快克使用者和 283 名多使用者）。使用成瘾严重程度指数第 6 版收集数据。我们的样本中观察到的 COVID-19 严重程度的最常见危险因素是：吸烟（82.5%）、动脉高血压（26.6%）、呼吸问题（23.4%）和无家可归史（25.1%）。动脉高血压和肝硬化在酒精使用者中更为常见。多使用者在街上生活的时间更长，艾滋病毒感染率高于酒精使用者。总体而言，样本中有 28%的人有三个或更多的危险因素。危险因素的频率很高，这种情况表明这些个体可能更容易出现更严重的 COVID-19 预后。因此，在大流行期间，针对物质使用者特定特征的预防策略值得关注。
