干扰素β在伴有子宫颈发育异常病变的尖锐湿疣中的活性。
Activity of interferon beta in condylomata with dysplastic lesion of the uterine cervix.
作者信息
Puligheddu P, Marcello C, Medda F, Parodo G, Setzu A, Lecca U
机构信息
Institute of Obstetrics and Gynecology, University of Cagliari, Italy.
出版信息
Eur J Gynaecol Oncol. 1988;9(2):161-2.
The effectiveness of interferon beta in the treatment of condylomata of the cervico-vaginal tract associated with CINs was evaluated in 25 patients. Human fibroblastic interferon (IFN beta) was administered by intra and perilesional infiltration at a dosage of 3 x 10(6) IU/day for 5 consecutive days the first week and every other day the second. The treatment showed: complete regression in 61.76% of CIN I and 58.69% of CIN II; partial regression in 26.47% of CIN I and 21.73% of CIN II. The picture remained unvaried in 11.76% of CIN I and 19.56% of CIN II.
对25例与宫颈上皮内瘤变（CIN）相关的宫颈阴道部湿疣患者评估了β干扰素的治疗效果。人成纤维细胞干扰素（IFNβ）通过瘤内和瘤周浸润给药，第一周剂量为3×10⁶IU/天，连续5天，第二周隔日给药。治疗结果显示：CIN I中有61.76%完全消退，CIN II中有58.69%完全消退；CIN I中有26.47%部分消退，CIN II中有21.73%部分消退。CIN I中有11.76%、CIN II中有19.56%病情无变化。
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