Rowland Institute at Harvard, 100 Edwin H Land Blvd, Cambridge, MA 02142, USA.
Rowland Institute at Harvard, 100 Edwin H Land Blvd, Cambridge, MA 02142, USA.
Curr Opin Microbiol. 2021 Jun;61:73-81. doi: 10.1016/j.mib.2021.02.005. Epub 2021 Apr 9.
Bacteria use a wide variety of flagellar architectures to navigate their environment. While the iconic run-tumble motility strategy of the peritrichously flagellated Escherichia coli has been well studied, recent work has revealed a variety of new motility behaviors that can be achieved with different flagellar architectures, such as single, bundled, or opposing polar flagella. The recent discovery of various flagellar gymnastics such as flicking and flagellar wrapping is increasingly shifting the view from flagella as passive propellers to versatile appendages that can be used in a wide range of conformations. Here, we review recent observations of how flagella shape motility behaviors and summarize the nascent structure-function map linking flagellation and behavior.
细菌利用各种各样的鞭毛结构来在环境中导航。虽然具有周生鞭毛的大肠杆菌的标志性奔跑-翻转运动策略已经得到了很好的研究，但最近的研究揭示了各种不同的鞭毛结构可以实现的新的运动行为，例如单根、束状或相反的极鞭毛。最近发现的各种鞭毛体操运动，如鞭毛弹动和鞭毛缠绕，正在逐渐将人们的观点从被动推进器的鞭毛转变为可以在广泛的构象中使用的多功能附属物。在这里，我们回顾了最近观察到的鞭毛如何塑造运动行为的情况，并总结了将鞭毛形成与行为联系起来的初生结构-功能图谱。
