Simon-Schnass I, Pabst H
Hermes Arzneimittel GmbH, medizinisch-wissenschaftliche Abteilung, Grosshesselohe/München.
Int J Vitam Nutr Res. 1988;58(1):49-54.
There are two properties of vitamin E which are leading to its use for better physical performance. On one side it promotes an economical energy metabolism, on the other side it acts as a stabilizing antioxidant in membranes. One group of 6 high altitude mountain climbers was substituted with 2 x 200 mg dl-alpha-tocopheryl acetate and a second of 6 were given placebos during a 10 weeks expedition. The influence on the synthesis of lactic acid and on the exhalation of pentane was investigated. After 2 weeks the anaerobic threshold (AT) was higher in both groups. In the course of the experiment the AT of the treatment group increased further whereas the AT of the control group decreased significantly (p less than 0.01). Pentane exhalation, considered to be a measure for lipid peroxidation, showed no significant change after a 4 weeks substitution with vitamin E in the treatment group, but in the control group the exhaled pentane was more than 100% higher. The difference is significant, too (p less than 0.01). The results of this study show that vitamin E has a beneficial effect on physical performance and on cell protection, at least at high altitude.
维生素E有两种特性使其被用于提升身体机能。一方面，它能促进经济的能量代谢，另一方面，它在细胞膜中起到稳定抗氧化剂的作用。一组6名高海拔登山者在为期10周的探险期间每天服用2×200毫克的dl-α-生育酚醋酸酯，另一组6人服用安慰剂。研究了对乳酸合成和戊烷呼出量的影响。两周后，两组的无氧阈值（AT）均升高。在实验过程中，治疗组的AT进一步升高，而对照组的AT显著下降（p<0.01）。戊烷呼出量被认为是脂质过氧化的一个指标，在治疗组用维生素E替代4周后，戊烷呼出量没有显著变化，但在对照组，呼出的戊烷高出100%以上。差异也很显著（p<0.01）。这项研究的结果表明，至少在高海拔地区，维生素E对身体机能和细胞保护有有益作用。
