David J Apple Center for Vision Research, Department of Ophthalmology, University Hospital Heidelberg, INF 400, 69120, Heidelberg, Germany.
Sci Rep. 2021 Apr 12;11(1):7968. doi: 10.1038/s41598-021-81772-w.
Implantation of toric intraocular lenses (IOLs) has become standard in the correction of corneal astigmatism. The IOL selection is based on keratometric measurements of the central cornea. However, mid-peripheral corneal changes may yield suboptimal correction in patients with larger pupils. This study retrospectively analyzed corneal topography data collected using a Scheimpflug device during routine clinical examinations. Of 11,953 patients, 641 met the inclusion criteria. Total corneal astigmatism was compared between five concentric zones (2-6 mm) using vector analysis. The absolute difference between astigmatism at 2 mm and 6 mm was 0.30 D (- 0.36 to 0.64), which decreased to 0.10 D (0 to 0.20) between the 5- and 6-mm zone. With-the-rule astigmatism was the most prevalent (53%), 34% had against-the-rule (ATR), and 13% had oblique. The decrease of the cylinder power with the diameter differed significantly between the three types, with ATR and oblique astigmatism being associated with the steepest change. Patients with high corneal astigmatism tend to demonstrate larger differences between the center and mid-periphery than those with low and moderate astigmatism. In conclusion, we demonstrated that central corneal astigmatism differs from that measured at the mid-periphery and that a larger difference was found in patients with ATR, oblique and high astigmatism.
角膜散光的矫正已成为有晶状体眼人工晶状体(IOL)植入术的标准。IOL 的选择基于中央角膜的角膜曲率计测量。然而,在瞳孔较大的患者中,周边角膜的中期变化可能导致矫正效果不佳。本研究回顾性分析了使用 Scheimpflug 设备在常规临床检查中收集的角膜地形图数据。在 11953 名患者中,有 641 名符合纳入标准。使用向量分析比较了五个同心区(2-6mm)的总角膜散光。2mm 和 6mm 处散光的绝对差值为 0.30D(-0.36 至 0.64),在 5-6mm 区之间降至 0.10D(0 至 0.20)。顺规散光最常见(53%),34%为逆规(ATR),13%为斜轴。随着直径的增加,散光力的下降在三种类型之间差异显著,ATR 和斜轴散光与最陡峭的变化相关。高角膜散光的患者倾向于比低和中度散光的患者在中心和周边之间表现出更大的差异。总之,我们证明中央角膜散光与周边测量的散光不同,ATR、斜轴和高散光患者的差异更大。