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眼部影像学在增强对年龄相关性黄斑变性的理解、评估和管理中的作用。

Ocular Imaging for Enhancing the Understanding, Assessment, and Management of Age-Related Macular Degeneration.

机构信息

Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA.

Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

出版信息

Adv Exp Med Biol. 2021;1256:33-66. doi: 10.1007/978-3-030-66014-7_2.

DOI:10.1007/978-3-030-66014-7_2
PMID:33847997
Abstract

Age-related macular degeneration (AMD) is a progressive neuro-retinal disease and the leading cause of central vision loss among elderly individuals in the developed countries. Modern ocular imaging technologies constitute an essential component of the evaluation of these patients and have contributed extensively to our understanding of the disease. A challenge with any review of ocular imaging technologies is the rapid pace of progress and evolution of these instruments. Nonetheless, for proper and optimal use of these technologies, it is essential for the user to understand the technical principles underlying the imaging modality and their role in assessing the disease in various settings. Indeed, AMD, like many other retinal diseases, benefits from a multimodal imaging approach to optimally characterize the disease. In this chapter, we will review the various imaging technologies currently used in the assessment and management of AMD.

摘要

年龄相关性黄斑变性(AMD)是一种进行性的神经视网膜疾病,也是发达国家中老年人视力丧失的主要原因。现代眼部成像技术是评估这些患者的重要组成部分,广泛促进了我们对该疾病的理解。任何眼部成像技术的评估都面临一个挑战,那就是这些仪器的快速发展和演进。尽管如此,为了正确和优化地使用这些技术,使用者理解成像方式背后的技术原理及其在各种情况下评估疾病的作用至关重要。实际上,AMD 与许多其他视网膜疾病一样,得益于多模态成像方法,从而可以最佳地对疾病进行特征描述。在本章中,我们将回顾目前用于评估和管理 AMD 的各种成像技术。

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本文引用的文献

1
Multimodal Imaging of Nonneovascular Age-Related Macular Degeneration.非新生血管性年龄相关性黄斑变性的多模态影像学
Invest Ophthalmol Vis Sci. 2018 Mar 20;59(4):AMD48-AMD64. doi: 10.1167/iovs.18-24158.
2
Quantity of Intraretinal Hyperreflective Foci in Patients With Intermediate Age-Related Macular Degeneration Correlates With 1-Year Progression.中间型年龄相关性黄斑变性患者视网膜内高反射灶的数量与 1 年进展相关。
Invest Ophthalmol Vis Sci. 2018 Jul 2;59(8):3431-3439. doi: 10.1167/iovs.18-24143.
3
Optical coherence tomography angiography.
光学相干断层扫描血管造影术。
Prog Retin Eye Res. 2018 May;64:1-55. doi: 10.1016/j.preteyeres.2017.11.003. Epub 2017 Dec 8.
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Understanding aneurysmal type 1 neovascularization (polypoidal choroidal vasculopathy): a lesson in the taxonomy of 'expanded spectra' - a review.了解动脉瘤样 1 型新生血管形成(息肉样脉络膜血管病变):“扩展谱”分类学的一个教训——综述。
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The Progression of Geographic Atrophy Secondary to Age-Related Macular Degeneration.年龄相关性黄斑变性继发的地图样萎缩进展。
Ophthalmology. 2018 Mar;125(3):369-390. doi: 10.1016/j.ophtha.2017.08.038. Epub 2017 Oct 27.
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The Definition, Rationale, and Effects of Thresholding in OCT Angiography.光学相干断层扫描血管造影中阈值处理的定义、基本原理及效果
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Fluorescence Lifetimes of Drusen in Age-Related Macular Degeneration.年龄相关性黄斑变性中玻璃膜疣的荧光寿命
Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4856-4862. doi: 10.1167/iovs.17-22184.
8
Alterations in the Choriocapillaris in Intermediate Age-Related Macular Degeneration.中年相关性黄斑变性中脉络膜毛细血管的改变。
Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4792-4798. doi: 10.1167/iovs.17-22360.
9
Green emission fluorophores in eyes with atrophic age-related macular degeneration: a colour fundus autofluorescence pilot study.萎缩性年龄相关性黄斑变性眼的绿色发射荧光团:一项彩色眼底自发荧光初步研究。
Br J Ophthalmol. 2018 Jun;102(6):827-832. doi: 10.1136/bjophthalmol-2017-310881. Epub 2017 Sep 25.
10
Green-Light Autofluorescence Versus Combined Blue-Light Autofluorescence and Near-Infrared Reflectance Imaging in Geographic Atrophy Secondary to Age-Related Macular Degeneration.绿光自体荧光与蓝光自体荧光联合近红外反射成像在年龄相关性黄斑变性继发地图样萎缩中的应用比较
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