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用于细胞标记和条形码识别的回音壁微激光器:体内生物传感的前景。

Whispering-gallery microlasers for cell tagging and barcoding: the prospects for in vivo biosensing.

作者信息

Toropov Nikita, Vollmer Frank

机构信息

Department of Physics and Astronomy, Living Systems Institute, University of Exeter, Exeter, EX4 4QD, UK.

出版信息

Light Sci Appl. 2021 Apr 14;10(1):77. doi: 10.1038/s41377-021-00517-6.

Abstract

Researchers in the field of whispering-gallery-mode (WGM) microresonators have proposed biointegrated low-threshold WGM lasers, to enable large-scale parallel single-cell tracking and barcoding. Although the reported devices have so far been primarily investigated in model applications, most recent results represent important steps towards the development of in vivo tags and sensors that utilize the unique and narrow spectral features of miniature WGM lasers.

摘要

回音壁模式(WGM)微谐振器领域的研究人员提出了生物集成低阈值WGM激光器,以实现大规模并行单细胞追踪和条形码识别。尽管迄今为止报道的器件主要在模型应用中进行了研究,但最新结果代表了利用微型WGM激光器独特且狭窄的光谱特征开发体内标签和传感器的重要进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56d/8046988/a3e0a6e39764/41377_2021_517_Fig1_HTML.jpg

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