Knobler E H, Silvers D N, Fine K C, Lefkowitch J H, Grossman M E
Department of Dermatology, College of Physicians and Surgeons, Columbia University, Columbia-Presbyterian Medical Center, New York.
JAMA. 1988;260(4):524-7.
We report four patients with antibodies to human immunodeficiency virus and/or acquired immunodeficiency syndrome who were noted to have unique vascular lesions that clinically resembled Kaposi's sarcoma or pyogenic granulomas. The lesions were asymptomatic erythematous-violaceous papules and nodules. They erupted over several weeks, without predilection for a specific cutaneous site. Most lesions resolved spontaneously. Histologically these lesions revealed a proliferation of vascular spaces lined by plump, cuboidal endothelial cells embedded in an edematous stroma with an inflammatory infiltrate. It is unclear if these lesions represent Kaposi's sarcoma or pyogenic granulomas or if they are distinct neoplasms associated with human immunodeficiency virus.
我们报告了4例患有人类免疫缺陷病毒抗体和/或获得性免疫缺陷综合征的患者，他们被发现有独特的血管病变，临床上类似于卡波西肉瘤或化脓性肉芽肿。这些病变为无症状的红斑性紫罗兰色丘疹和结节。它们在数周内出现，无特定皮肤部位的偏好。大多数病变可自发消退。组织学上，这些病变显示血管腔隙增生，内衬丰满的立方状内皮细胞，嵌入有炎症浸润的水肿基质中。尚不清楚这些病变是代表卡波西肉瘤或化脓性肉芽肿，还是与人类免疫缺陷病毒相关的独特肿瘤。
