GSEAplot：一个用于在 R 中定制基因集富集分析的软件包。
GSEAplot: A Package for Customizing Gene Set Enrichment Analysis in R.
机构信息
Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA.
出版信息
J Comput Biol. 2021 Jun;28(6):629-631. doi: 10.1089/cmb.2020.0426. Epub 2021 Apr 16.
Abstract
Gene Set Enrichment Analysis (GSEA) is used to identify differentially expressed gene sets that are enriched for annotated biological functions. The existing GSEA R code is not in the form of a flexible package with analysis and plotting customization options, and the results produced are not generated in the form of R objects. In this study, we introduce the GSEAplot R package with novel functionality for saving relevant information from the analysis to the current R workspace, and we introduce the ability to customize plots and databases. The GSEAplot package provides a novel utility that facilitates the implementation of GSEA R-based in genomics analysis pipelines.
摘要
基因集富集分析（GSEA）用于识别差异表达的基因集，这些基因集富含注释的生物学功能。现有的 GSEA R 代码不是一种具有分析和绘图自定义选项的灵活包，并且生成的结果不是以 R 对象的形式生成的。在本研究中，我们引入了 GSEAplot R 包，该包具有从分析中保存相关信息到当前 R 工作区的新功能，并引入了自定义绘图和数据库的功能。GSEAplot 包提供了一种新的实用程序，可方便地在基于基因组学分析管道的 GSEA R 中实施。
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