甲醛诱导的抗N抗体：肾移植失败的一个可能原因。
Formaldehyde induced anti-N: a possible cause of renal graft failure.
作者信息
Gorst D W, Riches R A, Renton P H
出版信息
J Clin Pathol. 1977 Oct;30(10):956-9. doi: 10.1136/jcp.30.10.956.
Abstract
Treatment of human red cells with low concentrations of formaldehyde induces an antigenic change which makes them react very strongly with the anti-N sera found in certain patients treated by haemodialysis. This supports the idea that formaldehyde sterilisation of reusable home dialysers leads to the development of anti-N in these patients' sera. The clinical problems produced by this antibody are discussed together with ways of overcoming them.
摘要
用低浓度甲醛处理人红细胞会引起抗原变化，使它们与某些接受血液透析治疗的患者血清中发现的抗 - N血清发生强烈反应。这支持了以下观点：可重复使用的家用透析器进行甲醛消毒会导致这些患者血清中产生抗 - N。本文讨论了这种抗体所产生的临床问题以及克服这些问题的方法。
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Anti-N-like antibodies in the sera of patients undergoing chronic hemodialysis.接受慢性血液透析患者血清中的抗N样抗体。
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