Department of Internal Medicine, Hospital de Especialidades "Dr. Antonio Fraga Mouret", Centro Médico Nacional La Raza Del Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
Department of Internal Medicine, Hospital General de Zona No.27 Del Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
Respir Med. 2021 May;181:106391. doi: 10.1016/j.rmed.2021.106391. Epub 2021 Apr 14.
The follow-up of recovered COVID-19 patients is still limited. We aimed to evaluate the changes in quality-of-life (QOL) and spirometric alterations in the convalescent phase of 115 patients with at least 30 days post-COVID-19.
We included patients with confirmed COVID-19 infection, available past medical records and at least 30 days after the onset of symptoms. All patients were asked to rate their general health condition before and after COVID-19 using the EQ-5D-5L standardized questionary and perform a spirometry at evaluation.
In this study, that included 70%(81/115) of patients with mild or moderate COVID-19; there was a severe decrease in QOL up to 56%(64/115). Alterations in usual activities and anxiety/depression were present in 59% of patients with a severe decrease in QOL. The persistence of symptoms was present in 63%(72/115). Restrictive lung impairment was the most common spirometric alteration in 17%(20/115), of whom 65%(13/20) had mild COVID-19.
Spirometric alterations are presented even in mild COVID-19, and more remarkably, there is a high rate of alterations in quality of life after the recovery of this disease.
对康复的 COVID-19 患者的随访仍然有限。我们旨在评估 115 例至少在 COVID-19 后 30 天的恢复期患者的生活质量（QOL）变化和肺功能改变。
我们纳入了有确诊 COVID-19 感染、有既往病历记录和至少 30 天症状后患者。所有患者均被要求使用 EQ-5D-5L 标准化问卷评估 COVID-19 前后的一般健康状况，并进行肺功能检查。
在这项研究中，70%（81/115）的患者为轻度或中度 COVID-19；高达 56%（64/115）的患者 QOL 严重下降。59%的 QOL 严重下降患者存在日常活动和焦虑/抑郁改变。63%（72/115）的患者存在症状持续存在。限制性肺功能障碍是最常见的肺功能改变，占 17%（20/115），其中 65%（13/20）为轻度 COVID-19。
即使是轻度 COVID-19 也会出现肺功能改变，更显著的是，这种疾病康复后生活质量的改变率很高。
