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蜂蜜及其主要成分对新冠病毒感染的潜在影响

Possible Potential Effects of Honey and Its Main Components Against Covid-19 Infection.

作者信息

Abedi Farshid, Ghasemi Saeedeh, Farkhondeh Tahereh, Azimi-Nezhad Mohsen, Shakibaei Mehdi, Samarghandian Saeed

机构信息

Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.

Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.

出版信息

Dose Response. 2021 Mar 30;19(1):1559325820982423. doi: 10.1177/1559325820982423. eCollection 2021 Jan-Mar.

Abstract

Coronavirus disease 2019 (COVID-19) is a viral pneumonia that is spreading rapidly worldwide. The main feature of this disease is a severe acute respiratory syndrome and caused by coronavirus 2 (SARS-CoV-2). There are several unknowns about the pathogenesis and therapeutically treatment of COVID-19 infection. In addition, available treatment protocols have not been effective in managing COVID-19 infection. It is proposed that natural anti-oxidants such as lemon, green tea, saffron, curcuma longa, etc. with high flavonoids like safranal, crocin, crocetin, catechins, resveratrol, calebin A, curcumin have therapeutic potential against viral infections. In this context, honey and its main components are being investigated as an option for patients with COVID-19. The present study may indicate that honey and its main components inhibit the entry of the virus into the host cell and its replication as well as modulate the inflammatory cascade. This review provides basic information for the possible potential effects of honey and its main components for fighting with SARS-CoV-2.

摘要

2019冠状病毒病(COVID-19)是一种正在全球迅速传播的病毒性肺炎。这种疾病的主要特征是严重急性呼吸综合征,由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起。关于COVID-19感染的发病机制和治疗方法仍有几个未知之处。此外,现有的治疗方案在管理COVID-19感染方面并不有效。有人提出,柠檬、绿茶、藏红花、姜黄等富含类黄酮(如藏红花醛、藏红花素、西红花酸、儿茶素、白藜芦醇、calebin A、姜黄素)的天然抗氧化剂对病毒感染具有治疗潜力。在此背景下,蜂蜜及其主要成分正作为COVID-19患者的一种选择进行研究。本研究可能表明,蜂蜜及其主要成分可抑制病毒进入宿主细胞及其复制,并调节炎症级联反应。本综述为蜂蜜及其主要成分对抗SARS-CoV-2的可能潜在作用提供了基本信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fec/8020257/6357a4624608/10.1177_1559325820982423-fig1.jpg

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