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大型医疗系统中COVID-19期间与阿片类药物相关的急诊科就诊情况

Opioid-related Emergency Department Visits During COVID-19 in a Large Health System.

作者信息

Hall Gavin T, Cruz Daniel S, Lank Patrick M, McCarthy Danielle M, Kim Howard S

机构信息

Department of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.

出版信息

J Addict Med. 2021;15(4):345-348. doi: 10.1097/ADM.0000000000000850.

Abstract

OBJECTIVE

Multiple states have reported increases in opioid overdose deaths during the coronavirus disease 2019 (COVID-19) pandemic, however little is known about opioid-related presentations to the emergency department (ED).

METHODS

This was a time series analysis of visits to 7 EDs in greater Chicago, Illinois from October 20, 2019 to July 25, 2020. We compared the number of ED visits for opioid-related diagnoses in the time period preceding the World Health Organization pandemic declaration (prepandemic period, October 20, 2019-July 3, 2020) to the time period following the World Health Organization declaration (pandemic period, March 8, 2020 to July 25, 2020) using a single-group interrupted time series analysis with Newey-West standard errors. We also present data on alcohol-related ED visits for comparison.

RESULTS

We evaluated a total of 177,405 visits across the 7 EDs during the study period. The mean number of weekly ED visits in the prepandemic and pandemic periods was 4841 and 4029 weekly visits, respectively. In the interrupted time series analysis, there was no significant immediate effect of the pandemic start on opioid-related ED visits (-0.44 visits per 1000 ED visits, 95% CI -2.47 to 1.58, P = 0.66), however, there was a significant immediate effect of the pandemic start on alcohol-related ED visits (-4.1, 95% CI: -8.25 to -0.01, P < 0.05).

CONCLUSIONS

Despite reductions in overall ED visit volumes and alcohol-related visits during COVID-19, the number of opioid-related visits was not significantly reduced during the early pandemic. These data reinforce the need to provide comprehensive treatment services for opioid use disorder during the co-occurring COVID-19 and opioid crises.

摘要

目的

多个州报告称,在2019冠状病毒病(COVID-19)大流行期间,阿片类药物过量死亡人数有所增加,然而,对于急诊科(ED)中与阿片类药物相关的就诊情况却知之甚少。

方法

这是一项对2019年10月20日至2020年7月25日期间伊利诺伊州大芝加哥地区7家急诊科就诊情况的时间序列分析。我们采用带有纽韦-韦斯特标准误的单组中断时间序列分析,比较了世界卫生组织宣布大流行之前的时间段(大流行前时期,2019年10月20日至2020年7月3日)和世界卫生组织宣布之后的时间段(大流行时期,2020年3月8日至2020年7月25日)中与阿片类药物相关诊断的急诊科就诊次数。我们还提供了与酒精相关的急诊科就诊数据以供比较。

结果

在研究期间,我们对7家急诊科的总计177405次就诊进行了评估。大流行前和大流行期间每周急诊科就诊的平均次数分别为每周4841次和4029次。在中断时间序列分析中,大流行开始对与阿片类药物相关的急诊科就诊没有显著的即时影响(每1000次急诊科就诊 -0.44次就诊,95%置信区间 -2.47至1.58,P = 0.66),然而,大流行开始对与酒精相关的急诊科就诊有显著的即时影响(-4.1,95%置信区间:-8.25至 -0.01,P < 0.05)。

结论

尽管在COVID-19期间总体急诊科就诊量和与酒精相关的就诊量有所减少,但在大流行早期,与阿片类药物相关的就诊次数并未显著减少。这些数据强化了在COVID-19和阿片类药物危机同时发生期间为阿片类药物使用障碍提供全面治疗服务的必要性。

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Estimating the uncertain effect of the COVID pandemic on drug overdoses.估算新冠大流行对药物过量的不确定影响。
PLoS One. 2023 Aug 10;18(8):e0281227. doi: 10.1371/journal.pone.0281227. eCollection 2023.

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