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剖宫产术后对儿童健康和发育是否有不良影响?我们能否 justifies 使用选择性剖宫产来预防产科盆底损伤?

Are there adverse outcomes for child health and development following caesarean section delivery? Can we justify using elective caesarean section to prevent obstetric pelvic floor damage?

机构信息

Pelvic Floor Unit, Westmead Hospital, Sydney, Australia.

出版信息

Int Urogynecol J. 2021 Jul;32(7):1963-1969. doi: 10.1007/s00192-021-04781-3. Epub 2021 Apr 20.

Abstract

INTRODUCTION AND HYPOTHESIS

Elective pre-labour Caesarean section (CS) delivery is widely regarded as the panacea for all pelvic floor dysfunction despite substantial epidemiological evidence that it is only partially protective. To demand a CS is also considered a right for the well-counselled patient, even without an elevated risk of incontinence or prolapse. In recent years there has been increasing data on possible adverse health outcomes for children delivered by CS over those delivered vaginally. This includes respiratory illness, atopic conditions, obesity, diabetes and other severe auto-immune diseases. Concern has also been raised over possible impacts on cognitive and neuropsychological development in these children. Often the response has been to dismiss these outcomes as a result of the indication for the CS birth such as antenatal compromise or maternal disease. However the marked increase in non-medical Caesarean delivery throughout many regions of the world has allowed us to better distinguish these contributing factors.

METHODS

This narrative review looks at some of the more recent evidence on adverse health and developmental outcomes associated with CS, particularly pre-labour CS and the implications for the long term health of our society.

RESULTS

Epidemiological studies and animal research indicate an increased risk of negative impacts on child physical health and neuro-cognitive development aftercaesarean section delivery, particularly pre-labour Caesarean section, compared with vaginal delivery. This elevated risk persists after correction forobstetric and maternal factors.

CONCLUSION

Caesarean section delivery can result in adverse outcomes for infant, maternal and societal wellbeing. Elective Caesarean section, purely to potentially minimise pelvic floor dysfunction, cannot be justified.

摘要

引言与假说

尽管有大量流行病学证据表明,选择性剖宫产(CS)分娩仅部分具有保护作用,但它被广泛认为是治疗所有盆底功能障碍的万灵药。即使没有失禁或脱垂的风险增加,要求剖宫产也被认为是经过充分咨询的患者的权利。近年来,关于剖宫产分娩的儿童可能出现的健康不良后果的证据越来越多,包括呼吸道疾病、特应性疾病、肥胖、糖尿病和其他严重的自身免疫性疾病。人们还对这些儿童的认知和神经心理发育可能受到的影响表示担忧。通常,对这些结果的反应是将其归因于 CS 分娩的指征,如产前并发症或母体疾病。然而,在世界许多地区,非医疗性剖宫产的明显增加使我们能够更好地区分这些促成因素。

方法

本叙述性综述探讨了与 CS 相关的一些较新的健康和发育不良结果的证据,特别是产前 CS 及其对我们社会长期健康的影响。

结果

流行病学研究和动物研究表明,与阴道分娩相比,剖宫产分娩后儿童身体健康和神经认知发育的负面影响风险增加,尤其是产前剖宫产。在纠正产科和母体因素后,这种风险仍然存在。

结论

剖宫产分娩会对婴儿、产妇和社会福利产生不良后果。仅仅为了潜在地减少盆底功能障碍而选择剖宫产分娩是不合理的。

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