Andersen L P, Elsborg L, Justesen T
Dept. of Enterovirus, Statens Seruminstitut, Copenhagen, Denmark.
Scand J Gastroenterol. 1988 Apr;23(3):347-50. doi: 10.3109/00365528809093877.
Only a few publications have dealt with the subjective symptoms, the paraclinical findings, or the epidemiology in relation to cultivation of C. pylori. Seventy-two patients answered a questionnaire containing questions about symptoms, dietary habits, smoking, and animal contact. C. pylori was cultivated from the biopsy specimens of 41 of these patients, and 31 were culture-negative. In addition, leukocyte count, differential count, and blood immunoglobulins were measured. In many culture-positive patients a variation in symptoms during the year was found, and symptoms had lasted more than 5 years. This was statistically significant for non-ulcer patients. In addition, we found initial abdominal pain and present vomiting to be significant features, but they did not seem to have any clinical significance. Unlike Marshall & Warren, we did not find ructus to be related to infections with C. pylori. In all other respects we found no differences between culture-negative and culture-positive patients. It was not possible to detect any descriptive variables in patients with C. pylori infections.
仅有少数出版物涉及与幽门螺杆菌培养相关的主观症状、临床旁检查结果或流行病学。72名患者回答了一份包含有关症状、饮食习惯、吸烟及动物接触问题的问卷。从其中41名患者的活检标本中培养出了幽门螺杆菌，31名患者培养结果为阴性。此外，还检测了白细胞计数、分类计数及血液免疫球蛋白。在许多培养阳性的患者中，发现其症状在一年中有变化，且症状持续超过5年。这在非溃疡患者中具有统计学意义。此外，我们发现初发腹痛和当前呕吐是显著特征，但它们似乎并无任何临床意义。与马歇尔和沃伦不同，我们未发现嗳气与幽门螺杆菌感染有关。在所有其他方面，我们未发现培养阴性和培养阳性患者之间存在差异。无法在幽门螺杆菌感染患者中检测到任何描述性变量。
