Harvey P D, Earle-Boyer E A, Levinson J C
Department of Psychiatry, Mt. Sinai Medical School, New York, NY 10029.
Schizophr Bull. 1988;14(1):57-66. doi: 10.1093/schbul/14.1.57.
Manic (n = 26), schizophrenic (n = 26), and normal (n = 25) subjects were examined with a digit span distraction task and with a reality monitoring task. All subjects were tested twice at a 4-day interval, and a clinical assessment of thought disorder was conducted both times on the patients. We found that reality monitoring, distraction task performance, and clinical thought disorder were all quite stable at the retest interval. We further found that different patterns of correlational relationships between cognitive deficits and positive and negative thought disorders were present in the manic and schizophrenic samples. When we conducted a cross-temporal analysis of our data, we found that no cognitive deficits in mania predicted the severity of positive thought disorder over time, although the severity of thought disorder predicted distraction performance over time. In the schizophrenic subjects, distraction performance, but not reality monitoring, exerted a significant cross-temporal influence on positive thought disorder.
对躁狂症患者(n = 26)、精神分裂症患者(n = 26)和正常受试者(n = 25)进行了数字广度分心任务和现实监测任务测试。所有受试者每隔4天测试两次,并且对患者进行了两次临床思维障碍评估。我们发现,在复测间隔期间,现实监测、分心任务表现和临床思维障碍都相当稳定。我们进一步发现,躁狂症和精神分裂症样本中存在认知缺陷与阳性和阴性思维障碍之间不同的相关关系模式。当我们对数据进行跨时间分析时,我们发现躁狂症中的认知缺陷并不能预测阳性思维障碍随时间的严重程度,尽管思维障碍的严重程度可以预测随时间的分心表现。在精神分裂症受试者中,分心表现而非现实监测对阳性思维障碍产生了显著的跨时间影响。