Department of Vision Sciences, School of Health & Life Sciences, Glasgow Caledonian University, Glasgow, United Kingdom.
School of Optometry &Vision Science, University of Bradford, Bradford, United Kingdom.
J Optom. 2022 Apr-Jun;15(2):129-137. doi: 10.1016/j.optom.2021.02.001. Epub 2021 Apr 18.
The purpose of this study was to extend the knowledge of peripheral biometric component and its relationship to refractive status in healthy individuals by determining the correlation between peripheral ocular length to peripheral corneal radius ratio and the refractive error.
This prospective study was conducted on thirty-three healthy adult participants. Refractive error was assessed objectively and subjectively and recorded as the mean spherical equivalent. Central and peripheral ocular lengths at 30° were assessed using partial coherence interferometry under dilation with 1% tropicamide. Central and peripheral corneal radius of curvature was assessed using Scheimpflug topography. Peripheral ocular lengths at 30° were paired with peripheral corneal curvatures at the incident points of the IOLMaster beam (3.8mm away from corneal apex) superiorly, inferiorly, temporally and nasally to calculate the peripheral ocular length-peripheral corneal radius ratio. Descriptive statistics were used to describe the distribution and spread of the data. Pearson's correlation analysis was used to present the association between biometric and refractive variables.
Refractive error was negatively correlated with the axial length-central corneal radius ratio (r=-0.91; p<0.001) and with 30° peripheral ocular length-peripheral corneal radius ratio in all four meridians (r≤-0.76; p<0.001). The strength of the correlation was considerably lower when only axial length or peripheral ocular lengths were used.
Using the ratios of peripheral ocular length-peripheral corneal radius to predict refractive error is more effective than using peripheral corneal radius or peripheral ocular length alone.
本研究旨在通过确定周边眼长与周边角膜半径比与屈光不正之间的相关性，扩展对健康个体周边生物测量组件及其与屈光状态关系的认识。
本前瞻性研究纳入了 33 名健康成年参与者。客观和主观评估屈光不正，并记录平均等效球镜度。使用散瞳后 1%托吡卡胺的部分相干干涉测量法评估 30°时的中央和周边眼长。使用 Scheimpflug topography 评估中央和周边角膜曲率半径。将 30°时的周边眼长与 IOLMaster 光束（距角膜顶点 3.8mm）入射点处的周边角膜曲率配对，以计算周边眼长-周边角膜半径比。使用描述性统计来描述数据的分布和离散程度。采用 Pearson 相关分析来呈现生物测量和屈光变量之间的关联。
屈光不正与眼轴-中央角膜半径比呈负相关（r=-0.91；p<0.001），与所有四个子午线上的 30°周边眼长-周边角膜半径比均呈负相关（r≤-0.76；p<0.001）。仅使用眼轴或周边眼长时，相关性的强度要低得多。
与单独使用周边角膜半径或周边眼长相比，使用周边眼长-周边角膜半径比来预测屈光不正更为有效。
