Cao Zhiwen, Jiao Lin, Wang Hongyu, Li Jun, Zhong Genping, Zhu Daocheng, Xu Wei, Jin MengKe
Jiangxi University of Traditional Chinese Medicine.
The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Medicine (Baltimore). 2021 Apr 23;100(16):e25388. doi: 10.1097/MD.0000000000025388.
Peripheral facial paralysis (PFP) is a common clinical neurological disease and the incidence of intractable peripheral facial paralysis is on the rise. Symptoms include crooked mouth and eyes, tearing and shallow nasolabial folds. The disease seriously affects the physical and mental health of patients. At present, a large number of clinical studies have shown that cupping is effective in treating intractable peripheral facial paralysis (IPFP). Therefore, the purpose of this review is to evaluate the effectiveness and safety of cupping in the treatment of refractory peripheral facial paralysis.
We will conduct a comprehensive and systematic search of relevant documents in the following databases: Medline, PubMed, the Cochrane Central Register of Controlled Trials (CENTRAL), Embase, Chinese Biomedical Literatures Database, China National Knowledge Infrastructure (CNKI), Wang Fang Database, Chinese Scientific Journal Database from inception to February 2021 without any language restriction. The 2 reviewers will be independently completed select research, extract data, evaluate research quality and use the Cochrane risk of bias tool to assess methodological quality. Using revman5.4 software for statistical analysis. The degree of heterogeneity will be Determined through heterogeneity test, to definite whether to adopt a random effects model or a fixed-effects model.
The protocol for the meta-analysis will systematically evaluate the efficacy and safety of cupping therapy for intractable peripheral facial paralysis patients.
This study will explore whether or not cupping therapy can be used as one of the non-drug therapies to prevent or treat intractable peripheral facial paralysis.
周围性面瘫是一种常见的临床神经系统疾病，难治性周围性面瘫的发病率呈上升趋势。症状包括口眼歪斜、流泪和鼻唇沟变浅。该疾病严重影响患者的身心健康。目前，大量临床研究表明，拔罐疗法在治疗难治性周围性面瘫方面是有效的。因此，本综述的目的是评估拔罐疗法治疗难治性周围性面瘫的有效性和安全性。
我们将对以下数据库中从建库至2021年2月的相关文献进行全面系统的检索：医学索引数据库（Medline）、医学期刊数据库（PubMed）、考克兰系统评价数据库（CENTRAL）、荷兰医学文摘数据库（Embase）、中国生物医学文献数据库、中国知网、万方数据库、维普中文科技期刊数据库，无语言限制。两名评价者将独立完成文献筛选、数据提取、研究质量评价，并使用考克兰偏倚风险工具评估方法学质量。使用RevMan5.4软件进行统计分析。通过异质性检验确定异质性程度，以确定采用随机效应模型还是固定效应模型。
本荟萃分析方案将系统评价拔罐疗法治疗难治性周围性面瘫患者的疗效和安全性。
本研究将探讨拔罐疗法是否可作为预防或治疗难治性周围性面瘫的非药物治疗方法之一。
