Department of Ultrasound, West China Hospital of Sichuan University, Chengdu, China.
Medicine (Baltimore). 2021 Apr 23;100(16):e25517. doi: 10.1097/MD.0000000000025517.
Primary schwannoma of the thyroid gland is very rare, and its preoperative diagnosis is difficult.
We report the case of a thyroid nodule in an 18-year-old woman, who presented with a mass in her left neck with stiffness and normal thyroid function. However, the patient complained of numbness in her left upper extremity, and ultrasound (US) features were suspicious of malignancy.
Multimodal US imaging was performed using B-mode, color doppler, ultrasonic elastography (UE), and contrast-enhanced ultrasound (CEUS). CEUS revealed heterogeneous enhancement and "target sign" within the tumor. The nodule was suspicious for malignancy and classified as TI-RADS 4b, while the elasticity values measured by UE indicated a benign lesion. Fine needle aspiration (FNA) was subsequently performed in the markedly contrast-enhanced area for biopsy. Cytological results revealed a benign schwannoma.
The patient underwent left lobe resection. Postoperative pathology confirmed it to be a primary benign schwannoma of the thyroid.
After thyroidectomy, the patient was followed-up with US. At present, all laboratory tests and thyroid imaging are normal, and the numbness of the left upper limb has disappeared.
The combination of different US modalities is useful for the diagnosis of thyroid lesions. FNA performed under CEUS guidance improves the accuracy of biopsy sampling.
甲状腺原发性神经鞘瘤非常罕见,术前诊断困难。
我们报告了 1 例 18 岁女性甲状腺结节病例,其主要表现为左侧颈部肿块伴僵硬,甲状腺功能正常。然而,患者诉左侧上肢麻木,超声(US)特征疑似恶性肿瘤。
采用 B 型、彩色多普勒、超声弹性成像(UE)和超声造影(CEUS)多模态 US 成像。CEUS 显示肿瘤内不均匀增强和“靶征”。结节恶性可能性大,TI-RADS 分类为 4b 类,UE 测量的弹性值提示良性病变。随后在明显增强区域进行细针抽吸(FNA)活检。细胞学结果显示为良性神经鞘瘤。
行左侧叶切除术。术后病理证实为甲状腺原发性良性神经鞘瘤。
甲状腺切除术后,患者接受 US 随访。目前,所有实验室检查和甲状腺成像均正常,左侧上肢麻木感消失。
不同 US 模式的联合有助于甲状腺病变的诊断。CEUS 引导下的 FNA 提高了活检采样的准确性。