Sun Yi, Jin Guangming, Yang Mengting, Fu Jing, Chen Xueyi, Lou Bingsheng
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
Department of Ophthalmology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.
J Ophthalmol. 2021 Apr 5;2021:8843032. doi: 10.1155/2021/8843032. eCollection 2021.
To investigate the prevalence, risk factors, and major causes of visual impairment (VI) in an elderly Chinese Uygur population in southern Xinjiang.
This was a population-based cross-sectional study. Participants aged 50 years and older from Haohan Country, Xinjiang Uygur Autonomous Region, were enrolled from August 2018 to December 2018 using cluster sampling. Participants underwent examinations including presenting visual acuity (PVA), pinhole vision, slit-lamp, intraocular pressure, and direct ophthalmoscopy. Participants' education and demographic information was collected by a questionnaire. The prevalence, risk factors, and major causes of vision loss were evaluated.
A total of 1465 participants (85.4% response rate) were enrolled. The mean age of the subjects was 59.1 ± 9.7 years. The prevalence of mild VI, moderate VI, severe VI, and blindness in the better eye was 13.3%, 12.8%, 2.9%, and 3.4%, respectively. The prevalence of low vision and blindness in this study was higher than that in Altay & Tacheng and Changji in northern Xinjiang, lower than that in Luxi, and similar to that in Tibet. The multiple logistic regression analysis showed that age, education level, and body mass index (BMI) were significantly associated with low vision and blindness ( ≤ 0.001, <0.05, 0.002, respectively). The major causes of low vision were cataract (42.6%), refractive error (19.6%), and glaucoma (12.6%), whereas the primary causes of blindness were cataract (34%), glaucoma (34%), and retinitis pigmentosa (10%).
VI is an important public health issue among elderly Uygur individuals in the area, especially for those with low education levels. Cataract is the leading cause of low vision and blindness.
调查中国新疆南部维吾尔族老年人群中视力损害（VI）的患病率、危险因素及主要病因。
这是一项基于人群的横断面研究。采用整群抽样方法，于2018年8月至2018年12月纳入新疆维吾尔自治区浩罕县50岁及以上的参与者。参与者接受了包括裸眼视力（PVA）、针孔视力、裂隙灯、眼压和直接检眼镜检查。通过问卷调查收集参与者的教育程度和人口统计学信息。评估视力丧失的患病率、危险因素及主要病因。
共纳入1465名参与者（应答率85.4%）。受试者的平均年龄为59.1±9.7岁。较好眼的轻度VI、中度VI、重度VI和失明的患病率分别为13.3%、12.8%、2.9%和3.4%。本研究中低视力和失明的患病率高于新疆北部的阿勒泰&塔城和昌吉，低于泸西，与西藏相似。多因素logistic回归分析显示，年龄、教育程度和体重指数（BMI）与低视力和失明显著相关（分别为≤0.001、<0.05、0.002）。低视力的主要病因是白内障（42.6%）、屈光不正（19.6%）和青光眼（12.6%），而失明的主要病因是白内障（34%）、青光眼（34%）和视网膜色素变性（10%）。
VI是该地区维吾尔族老年人中的一个重要公共卫生问题，尤其是对于教育程度较低的人群。白内障是低视力和失明的主要原因。
