Nofouzi Katayoon, Mirzazadeh Sorayya, Khordadmehr Monireh, Madadi Mohammad Sadegh, Amininia Soheila, Firouzamandi Masoumeh, Ranjbar Vahid Reza
Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
Iran J Microbiol. 2021 Feb;13(1):81-90. doi: 10.18502/ijm.v13i1.5496.
species are Gram-positive rods that exist in a broad range of environments. In this study, the efficacy of heat-killed on growth performance, intestinal morphology, and humoral immune responses of broiler chicken was evaluated.
Ross broiler chicks in the cage were randomly allocated to five groups. Trail diets were prepared by adding 10 cells per bird of heat-killed into the basal trading diet for group 1 continuously dosed for 24 h from day 1 to day 13, and for group 2, 24 h on days 1 to 5; 8; 9, 12 and 13. Group 3 was received 10 bacteria as a subcutaneous injection on days 1, 6, and 12. Groups 4 and 5 were not received during the experiment period.
Feed intake (FI) and feed conversion ratio (FCR) were not altered by different delivery methods of supplementation. The pulsed dosed in feed tended to provide higher body weight gain (BWG) than the negative control groups. treatments, never less of the ways of delivery, boosted (P<0.05) the antibody titers to Newcastle disease virus (NDV), and avian influenza (AI) (H9N2) virus, especially when broiler chickens treated with pulse dosed in the feed. The most significant intestinal development (p<0.05) was observed between groups 1 and 2. There were no significant differences in the thymus, liver, and bursa of Fabricius relative weight. Still, there were significant increases in the relative weight of spleen on day 14 in vaccinated chickens treated with pulse dosed.
It seems that the supplementation of in the broiler diet can improve intestinal morphology and humoral immune response, which was represented by increased antibody response to NDV, and AI vaccines significantly, but it cannot affect FI and FCR.
[某种细菌名称]为革兰氏阳性杆菌，广泛存在于多种环境中。本研究评估了热灭活[某种细菌名称]对肉鸡生长性能、肠道形态及体液免疫反应的影响。
笼养的罗斯肉鸡雏鸡随机分为五组。在基础日粮中每只鸡添加10个热灭活[某种细菌名称]细胞制备试验日粮，第1组从第1天至第13天连续24小时投喂，第2组在第1至5天、第8天、第9天、第12天和第13天各投喂24小时。第3组在第1天、第6天和第12天皮下注射10个细菌。第4组和第5组在实验期间不给予[某种细菌名称]。
不同的[某种细菌名称]添加方式未改变采食量（FI）和饲料转化率（FCR）。饲料中脉冲式添加[某种细菌名称]组的体重增加（BWG）高于阴性对照组。无论采用何种添加方式，[某种细菌名称]处理均提高了（P<0.05）对新城疫病毒（NDV）和禽流感（AI）（H9N2）病毒的抗体滴度，尤其是饲料中脉冲式添加[某种细菌名称]处理的肉鸡。第1组和第2组之间观察到最显著的肠道发育（p<0.05）。胸腺、肝脏和法氏囊的相对重量无显著差异。然而，脉冲式添加[某种细菌名称]处理的免疫鸡在第14天脾脏相对重量显著增加。
肉鸡日粮中添加[某种细菌名称]似乎可改善肠道形态和体液免疫反应，表现为对NDV和AI疫苗的抗体反应显著增加，但不影响FI和FCR。
