Cui Yan, Meng Weishuang, He Feng, Chen Zeliang, Liu Hongliang, Li Desheng
College of Husbandry and Veterinary Medicine, Jinzhou Medical University, Jinzhou, China.
Key Laboratory of Animal Product Quality and Safety of Liaoning Province, Jinzhou Medical University, Jinzhou, China.
Front Microbiol. 2025 Jun 27;16:1606352. doi: 10.3389/fmicb.2025.1606352. eCollection 2025.
At present, has been reported as a probiotic to be used as a feed additive to improve the production performance of broilers. However, the relevant reports on its derived postbiotics are still limited.
In this study, a total of 480 day-old Arbor acre broiler chicks with an initial body weight of 52.8 ± 1.4 g were used in this study to investigate the effects of dietary supplementation of graded levels of heat-killed on growth performance, cecal morphology, and cecal bacteria and fungus composition. Birds were assigned into four groups with six replicates of 20 birds each. The experiment was designed to last for 42 days. was supplemented with 0.000, 0.015, 0.030, or 0.045% heat-killed (HKB).
Our data indicate that body weight gain, gain to feed ratio, cecal villus height, and cecal villus to crypt ratio dose-dependently improved, while cecal crypt depth dose-dependently reduced, by HKB supplementation. Additionally, dietary supplementation of graded levels of HKB dose-dependently reduced cecal bacteria Chao1 index. Cecal bacteria identified by 16S rRNA and cecal fungus identified by ITS revealed that the supplementation of HKB regulate the composition of bacteria and fungus in cecum.
Therefore, dietary supplementation of HKB is an effective measure to improve cecal morphology by regulating cecal bacteria and fungus composition, and therefore improved growth performance.
目前，已报道 作为一种益生菌用作饲料添加剂以提高肉鸡的生产性能。然而，关于其衍生后生元的相关报道仍然有限。
在本研究中，总共480只1日龄爱拔益加肉鸡雏鸡，初始体重为52.8±1.4克，用于研究日粮中添加不同水平热灭活 对生长性能、盲肠形态以及盲肠细菌和真菌组成的影响。将鸡分为四组，每组六个重复，每个重复20只鸡。实验设计持续42天。分别添加0.000%、0.015%、0.030%或0.045%的热灭活 （HKB）。
我们的数据表明，添加HKB可使体重增加、料重比、盲肠绒毛高度和盲肠绒毛与隐窝比值呈剂量依赖性提高，而盲肠隐窝深度呈剂量依赖性降低。此外，日粮中添加不同水平的HKB可使盲肠细菌Chao1指数呈剂量依赖性降低。通过16S rRNA鉴定的盲肠细菌和通过ITS鉴定的盲肠真菌表明，添加HKB可调节盲肠中细菌和真菌的组成。
因此，日粮中添加HKB是通过调节盲肠细菌和真菌组成来改善盲肠形态从而提高生长性能的有效措施。
