Bomholt A
University ENT Department, Gentofte Hospital, Hellerup, Denmark.
Acta Otolaryngol. 1988 Mar-Apr;105(3-4):367-71. doi: 10.3109/00016488809097020.
All 23 patients treated for juvenile laryngeal papillomatosis (JLP) in the Copenhagen region during a 4-year-period were identified for this epidemiological study. The incidence of JLP was 0.6/100,000 among the population at risk, children aged 0-14 years, and the prevalence was 0.8/100,000. It is concluded that the condition in most cases has a good prognosis, i.e., short duration and low morbidity. Only in a few cases JLP will take a long-lasting course. Regression before or during puberty does not in all cases ensure complete recovery. Thus, 7 of 12 adult patients experienced a quiescent period of 21 years (median). Spread of papillomas to the bronchogenic system seems to be a serious prognostic sign.
在一项为期4年的流行病学研究中，确定了哥本哈根地区所有23例接受青少年喉乳头状瘤病（JLP）治疗的患者。在0至14岁有患病风险的儿童人群中，JLP的发病率为0.6/10万，患病率为0.8/10万。得出的结论是，在大多数情况下，该病预后良好，即病程短且发病率低。只有少数情况下JLP病程会持续较长时间。青春期前或青春期期间的病情消退并非在所有情况下都能确保完全康复。因此，12例成年患者中有7例经历了长达21年（中位数）的静止期。乳头状瘤扩散至支气管系统似乎是一个严重的预后指标。
