Department of Ophthalmology, Lady Hardinge Medical College and Associated Hospitals, University of Delhi, New Delhi, India.
Department of Ophthalmology, University College of Medical Sciences and Associated GTB Hospital, University of Delhi, New Delhi, India.
Eur J Ophthalmol. 2021 Nov;31(6):2818-2827. doi: 10.1177/11206721211009447. Epub 2021 Apr 23.
Ischaemic optic neuropathy (ION) is a major cause of blindness. The clinical approach and management is a matter of debate for the treating neurologist and the ophthalmologist. Of the two broad varieties namely the posterior (PION) and anterior ischaemic optic neuropathy (AION), the arteritic variety of the AION (AAION) is usually due to giant cell arteritis. Giant cell arteritis may only present with visual loss in up to 25% of cases. AAION is a neuro-ophthalmic emergency. Early recognition and differentiation from AAION is imperative in order to prevent further devastating visual loss. A literature search was conducted on pubmed using key words as AAION, arteritic anterior ischaemic optic neuropathy, giant cell arteritis (GCA) and articles from the year 2000 till date were included. In any case very few reviews are available on AAION. The literature search on pubmed provided holistic overview about this clinical significant entity and the same is compiled in this review. Moreover the histopathologic features of a temporal artery biopsy have been described with its microscopic images. In any case reviews are mostly available on the Non arteritic variety of AION. This review recapitulates the diagnostic and management protocol of a patient presenting with AAION.
缺血性视神经病变（ION）是失明的主要原因。对于治疗神经病学家和眼科医生来说，临床方法和管理是一个有争议的问题。在两种广泛的类型中，即后部（PION）和前部缺血性视神经病变（AION）中，AION 的动脉炎性类型（AAION）通常是由于巨细胞动脉炎引起的。高达 25%的巨细胞动脉炎病例可能仅表现为视力丧失。AAION 是一种神经眼科急症。为了防止进一步的严重视力丧失，早期识别和区分 AAION 至关重要。使用 AAION、动脉炎性前部缺血性视神经病变、巨细胞动脉炎（GCA）等关键词在 pubmed 上进行了文献检索，并纳入了 2000 年至今的文章。在任何情况下，关于 AAION 的综述都很少。在 pubmed 上进行的文献检索提供了对这一具有临床意义实体的全面概述，并在本综述中进行了汇编。此外，还描述了颞动脉活检的组织病理学特征，并附有其显微镜图像。在任何情况下，关于 AION 的非动脉炎性类型的综述都很多。本综述回顾了出现 AAION 的患者的诊断和管理方案。
