School of Chemistry & Chemical Engineering, Hubei University, Wuhan 430062, China; Department of Science & Engineering, Novel Global Community Educational Foundation, NSW, Australia.
Department of Food Science & Nutrition Management, J.D.Birla Institute, Kolkata, West Bengal, India.
Exp Gerontol. 2021 Jul 15;150:111352. doi: 10.1016/j.exger.2021.111352. Epub 2021 Apr 21.
Old age is viewed as an unavoidable, undesirable, and problem-ridden phase of life. As people age, they become more susceptible to disease and disability due to various factors like low immunity, decreased functionality of cells, DNA damage, higher incidence of inflammation, etc. Healthy aging is very important. The nutrition and health of the elderly is often neglected. Nutritional interventions could play an important part in the prevention of degenerative conditions of the elderly and an improvement of their quality of life. The medicinal properties of plants are always believed for its therapeutic effect and its efficiency in treating many without adverse effects. The role of phytomedicine in aging is very crucial as it possesses important bioactive compounds and constituents (such as polyphenols, flavonoids, phenolic acids, and others) which are considered to provide anti-aging properties as well as helps in reducing age-associated problems. Some natural leaves such as Moringa oleifera, curry leaves, guava leaves, green tea, olive leaves, Ginkgo biloba, thankuni leaves, grape leaves, vasaka leaves, and kulekhara leaves are found to have therapeutic effects against diseases like cancer, diabetes, immunosuppression, hepatic damage, and neurodegenerative disorders. Hence, this review aims at understanding the effectiveness of these natural products in curing the geriatric population and the mechanism by which the therapeutic effects are exerted by them.
衰老被视为生命中不可避免、不理想且问题重重的阶段。随着年龄的增长,由于免疫力低下、细胞功能下降、DNA 损伤、炎症发生率升高等各种因素,人们更容易患上疾病和残疾。健康老龄化非常重要。老年人的营养和健康往往被忽视。营养干预可能在预防老年人退行性疾病和提高他们的生活质量方面发挥重要作用。人们一直相信植物的药用特性具有治疗效果,并且在治疗许多疾病方面没有副作用。植物药在衰老中的作用非常关键,因为它含有重要的生物活性化合物和成分(如多酚、类黄酮、酚酸等),被认为具有抗衰老特性,并有助于减少与年龄相关的问题。一些天然叶子,如辣木、咖喱叶、番石榴叶、绿茶、橄榄油叶、银杏叶、檀香叶、葡萄叶、瓦萨卡叶和苦楝叶,被发现对癌症、糖尿病、免疫抑制、肝损伤和神经退行性疾病等疾病具有治疗作用。因此,本综述旨在了解这些天然产品治疗老年人群体的有效性,以及它们发挥治疗作用的机制。