Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Fašmon Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Brantom Paul, Chesson Andrew, Westendorf Johannes, Manini Paola, Pizzo Fabiola, Dusemund Birgit
EFSA J. 2021 Apr 21;19(4):e06525. doi: 10.2903/j.efsa.2021.6525. eCollection 2021 Apr.
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of a dried extract prepared from the leaves of L. ( dry extract) when used as a sensory additive in feed for cats and dogs. dry extract is specified to contain at least 24% flavonol glycosides, at least 6% terpene lactones and less than 5 ppm ginkgolic acids. Since uncertainty remains concerning the nature of up to 75% of the extract, the additive is not sufficiently characterised to allow an assessment based on the individual components. In view of the indication of potential carcinogenicity from the results of studies by the National Toxicology Program of the USA, obtained with a extract comparable with the additive under assessment, the FEEDAP Panel concludes that the additive cannot be considered safe for cats and dogs. In the absence of data, no conclusions can be drawn on the safety for the user. In the absence of evidence that the extract acts as a flavour in animal feed or has an effect on palatability, the FEEDAP Panel was unable to conclude on the efficacy of the additive.
应欧盟委员会的要求，动物饲料添加剂和产品或物质专家小组（FEEDAP）被要求就从L.的叶子中制备的干燥提取物（干燥提取物）用作猫和狗饲料中的感官添加剂时的安全性和有效性发表科学意见。干燥提取物规定含有至少24%的黄酮醇苷、至少6%的萜烯内酯和少于5 ppm的银杏酸。由于高达75%的提取物的性质仍存在不确定性，该添加剂的特征不足以基于单个成分进行评估。鉴于美国国家毒理学计划的研究结果表明与所评估的添加剂相当的提取物具有潜在致癌性，FEEDAP小组得出结论，该添加剂对猫和狗不安全。在缺乏数据的情况下，无法就对使用者的安全性得出结论。由于没有证据表明该提取物在动物饲料中起调味作用或对适口性有影响，FEEDAP小组无法就该添加剂的有效性得出结论。
