Eddicks Matthias, Eddicks Lina, Stadler Julia, Hermanns Walter, Ritzmann Mathias
Klinik für Schweine, Zentrum für Klinische Tiermedizin, Ludwig-Maximilians-Universität München.
Institut für Tierpathologie, Zentrum für Klinische Tiermedizin, Ludwig-Maximilians-Universität München.
Tierarztl Prax Ausg G Grosstiere Nutztiere. 2021 Apr;49(2):120-132. doi: 10.1055/a-1403-1976. Epub 2021 Apr 26.
The porcine respiratory disease complex describes a clinical condition that often manifests as treatment-resistant respiratory disease of growing to finishing pigs. Its multifactorial etiology includes infectious and non-infectious factors. Besides management and hygiene conditions, particularly viral and bacterial pathogens contribute to the development and course of PRDC. The porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), influenza A virus (IAV) and () are considered as the major pathogens involved in PRDC. The clinical outcome and necropsy findings may differ depending on the involvement of the different pathogens. The complex nature of the PRDC impedes the diagnostic and preventive measures on affected farms. The present review provides insight into the pathomorphology, pathogenesis and inter-pathogen-interactions and aims to support practitioners in implementing purposeful diagnostic and preventive measures.
猪呼吸道疾病综合征描述的是一种临床病症，通常表现为生长育肥猪的难治性呼吸道疾病。其多因素病因包括感染性和非感染性因素。除管理和卫生条件外，特别是病毒和细菌病原体促成了猪呼吸道疾病综合征的发生发展过程。猪繁殖与呼吸综合征病毒（PRRSV）、猪圆环病毒2型（PCV2）、甲型流感病毒（IAV）和（）被认为是参与猪呼吸道疾病综合征的主要病原体。临床结果和尸检结果可能因不同病原体的参与情况而有所不同。猪呼吸道疾病综合征的复杂性阻碍了对受影响猪场的诊断和预防措施。本综述深入探讨了病理形态学、发病机制和病原体间相互作用，旨在支持从业者实施有针对性的诊断和预防措施。
