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Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity.

作者信息

He Zhenyu, Chen Kangjing, Ye Youpi, Chen Zhucheng

机构信息

Key Laboratory for Protein Sciences of Ministry of Education, School of Life Science, Tsinghua University, Beijing 100084, China.

Beijing Advanced Innovation Center for Structural Biology and Beijing Frontier Research Center for Biological Structure, School of Life Science, Tsinghua University, Beijing 100084, China.

出版信息

Cell Discov. 2021 Apr 27;7(1):28. doi: 10.1038/s41421-021-00262-5.

DOI:10.1038/s41421-021-00262-5
PMID:33907182
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8079448/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3ff/8079448/b1f7675fe9af/41421_2021_262_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3ff/8079448/b1f7675fe9af/41421_2021_262_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3ff/8079448/b1f7675fe9af/41421_2021_262_Fig1_HTML.jpg

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Mol Cell. 2020 Nov 19;80(4):712-725.e5. doi: 10.1016/j.molcel.2020.09.024. Epub 2020 Oct 14.
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Structure of the yeast Swi/Snf complex in a nucleosome free state.酵母 Swi/Snf 复合物在无核小体状态下的结构。
Nat Commun. 2020 Jul 7;11(1):3398. doi: 10.1038/s41467-020-17229-x.
3
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Nat Commun. 2025 Apr 17;16(1):3675. doi: 10.1038/s41467-025-58795-2.
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The Histomorphology to Molecular Transition: Exploring the Genomic Landscape of Poorly Differentiated Epithelial Endometrial Cancers.从组织形态学到分子转变:探索低分化子宫内膜上皮癌的基因组格局
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Beyond the mono-nucleosome.超越单核小体。
Biochem Soc Trans. 2025 Jan 31;53(1):BCJ20240452. doi: 10.1042/BST20230721.
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Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1.染色质重塑因子Snf22和Sol1功能缺失突变对肌醇焦磷酸中毒的抑制作用以及对裂殖酵母调控子的过度抑制
mBio. 2024 Jul 17;15(7):e0125224. doi: 10.1128/mbio.01252-24. Epub 2024 Jun 20.
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