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经肝动脉放射栓塞治疗肝细胞癌后的治疗反应评估。

Treatment response assessment following transarterial radioembolization for hepatocellular carcinoma.

机构信息

Department of Radiology, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.

Department of Abdominal Imaging, University of Texas M.D. Anderson Cancer Centre, Houston, USA.

出版信息

Abdom Radiol (NY). 2021 Aug;46(8):3596-3614. doi: 10.1007/s00261-021-03095-8. Epub 2021 Apr 28.

DOI:10.1007/s00261-021-03095-8
PMID:33909092
Abstract

Transarterial radioembolization with yttrium-90 microspheres is an established therapy for hepatocellular carcinoma. Post-procedural imaging is important for the assessment of both treatment response and procedural complications. A variety of challenging treatment-specific imaging phenomena complicate imaging assessment, such as changes in tumoral size, tumoral and peritumoral enhancement, and extrahepatic complications. A review of the procedural steps, emerging variations, and timelines for post-treatment tumoral and extra-tumoral imaging changes are presented, which may aid the reporting radiologist in the interpretation of post-procedural imaging. Furthermore, a description of post-procedural complications and their significance is provided.

摘要

经动脉放射性栓塞术用钇-90 微球是治疗肝细胞癌的一种成熟疗法。术后影像学检查对于评估治疗反应和手术并发症都很重要。各种具有挑战性的特定于治疗的影像学现象使影像学评估变得复杂,例如肿瘤大小、肿瘤和肿瘤周围增强以及肝外并发症的变化。本文回顾了治疗步骤、新兴的变化以及治疗后肿瘤和肿瘤外影像学变化的时间线,这可能有助于报告放射科医生解读术后影像学。此外,还描述了术后并发症及其意义。

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本文引用的文献

1
MRI Assessment of Hepatocellular Carcinoma after Local-Regional Therapy: A Comprehensive Review.MRI 评估局部区域治疗后肝细胞癌:全面综述。
Radiol Imaging Cancer. 2020 Jan 31;2(1):e190024. doi: 10.1148/rycan.2020190024. eCollection 2020 Jan.
2
Predictors of Complete Response in Patients with Hepatocellular Carcinoma Treated with Trans-Arterial Radioembolization.经动脉放射栓塞治疗肝细胞癌患者完全缓解的预测因素。
Curr Oncol. 2021 Feb 21;28(1):965-977. doi: 10.3390/curroncol28010095.
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Diagnostic and prognostic value of Tc-MAA SPECT/CT for treatment planning of Y-resin microsphere radioembolization for hepatocellular carcinoma: comparison with planar image.
Ther Adv Med Oncol. 2024 Sep 30;16:17588359241280692. doi: 10.1177/17588359241280692. eCollection 2024.
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Percutaneous thermal segmentectomy for liver malignancies over 3 cm: mid-term oncological performance and predictors of sustained complete response from a multicentric Italian retrospective study.经皮热段切除术治疗 3cm 以上肝脏恶性肿瘤:来自意大利多中心回顾性研究的中期肿瘤学结果和持续完全缓解的预测因素。
Radiol Med. 2024 Oct;129(10):1543-1554. doi: 10.1007/s11547-024-01877-w. Epub 2024 Sep 16.
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Role of interventional oncology in hepatocellular carcinoma: Future best practice beyond current guidelines.介入肿瘤学在肝细胞癌中的作用:超越当前指南的未来最佳实践。
Br J Radiol. 2022 Sep 1;95(1138):20220379. doi: 10.1259/bjr.20220379. Epub 2022 Aug 4.
Tc-MAA SPECT/CT 对 Y 树脂微球放射性栓塞治疗肝细胞癌的治疗计划的诊断和预后价值:与平面图像比较。
Sci Rep. 2021 Feb 5;11(1):3207. doi: 10.1038/s41598-021-82887-w.
4
Safety and efficacy of repeat Y90 radioembolization to the same hepatic arterial territory.同一肝动脉区域内重复 Y90 放射性栓塞的安全性和有效性。
Br J Radiol. 2021 Mar 1;94(1119):20200752. doi: 10.1259/bjr.20200752. Epub 2021 Jan 7.
5
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World J Hepatol. 2020 Oct 27;12(10):738-753. doi: 10.4254/wjh.v12.i10.738.
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Eur J Nucl Med Mol Imaging. 2021 Feb;48(2):580-583. doi: 10.1007/s00259-020-04976-8. Epub 2020 Aug 4.
9
Safety and efficacy of radioembolization with glass microspheres in hepatocellular carcinoma patients with elevated lung shunt fraction: analysis of a 103-patient cohort.玻璃微球放射性栓塞术在肺分流分数升高的肝细胞癌患者中的安全性和有效性:对103例患者队列的分析
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