Medical Education Unit, Walter Sisulu University, Mthatha, South Africa.
Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
AIDS Res Ther. 2023 Feb 6;20(1):6. doi: 10.1186/s12981-022-00498-5.
Psychological distress as measured by mental disorders like depression and anxiety is more prevalent in people living with HIV (PLHIV) than in the general population. However, the relationship between mental disorders and HIV is complex and bidirectional. Improved understanding of the relationship between mental disorders and HIV is important for designing interventions for this group. This paper explores the interrelationships of psychological distress with HIV and associated socio-demographic and health-related factors.
This secondary data analysis used the 2012 South African population-based household survey on HIV collected using a cross-sectional multi-stage stratified cluster sampling design. Generalized structural equation modelling (G-SEM) path analysis was used to explore the direct and indirect relationships of socio-demographic, health and HIV-related factors with psychological distress as measured by Kessler 10 scale using HIV status as a moderator variable.
A total of 20,083 participants were included in the study, 21.7% reported psychological distress, of whom (32.6%) were HIV positive. In the final path model with HIV status as a moderator, psychological distress was significantly more likely among age group 25-49 years (AOR: 1.4 [95% CI 1.3-1.6]), age 50 years and older, (AOR: 1.4 [95% CI 1.2-1.6]), females (AOR: 1.6 [95% CI 1.4-1.8]), high risk drinkers (AOR: 1.9 [1.6-2.2]) hazardous drinkers (AOR: 4.4 [95% CI 3.1-6.3]), ever tested for HIV (AOR: 1.2 [95% CI 1.1-1.3]). Psychological distress was significantly less likely among the married [AOR: 0.8 (0.7-0.9)], other race groups [AOR: 0.5 (0.5-0.6)], those with secondary level education (AOR: 0.9 [95% CI 0.8-0.9]), and tertiary level education (AOR: 0.7 [95% CI 0.6-0.9]), those from rural informal [AOR: 0.8 (0.7-0.9)], and rural formal [AOR: 0.8 (0.7-0.9)] areas and those who rated their health as excellent/good [AOR: 0.4 (0.4-0.5)].
The findings highlight the importance of designing tailored interventions targeted at psychological distress among PLHIV especially the elderly, females, those with no education and / or low education attainment and those residing in informal urban areas.
与普通人群相比,HIV 感染者(PLHIV)中出现心理健康障碍(如抑郁和焦虑)等心理困扰的比例更高。然而,心理健康障碍与 HIV 之间的关系是复杂且双向的。深入了解心理健康障碍与 HIV 之间的关系,对于为这一群体设计干预措施非常重要。本文探讨了心理健康障碍与 HIV 以及相关社会人口学和健康相关因素之间的相互关系。
本二次数据分析使用了 2012 年南非基于人群的家庭 HIV 调查数据,该调查采用了横断面多阶段分层聚类抽样设计。使用广义结构方程模型(G-SEM)路径分析,以 Kessler 10 量表衡量的心理困扰为因变量,以 HIV 状态为调节变量,探索社会人口学、健康和 HIV 相关因素与心理困扰的直接和间接关系。
本研究共纳入 20083 名参与者,其中 21.7%报告存在心理困扰,其中(32.6%)HIV 阳性。在 HIV 状态作为调节变量的最终路径模型中,25-49 岁年龄组(AOR:1.4 [95% CI 1.3-1.6])、50 岁及以上年龄组(AOR:1.4 [95% CI 1.2-1.6])、女性(AOR:1.6 [95% CI 1.4-1.8])、高风险饮酒者(AOR:1.9 [1.6-2.2])、危险饮酒者(AOR:4.4 [95% CI 3.1-6.3])、曾接受过 HIV 检测(AOR:1.2 [95% CI 1.1-1.3])者出现心理困扰的可能性显著更高。已婚者(AOR:0.8 [0.7-0.9])、其他种族群体(AOR:0.5 [0.5-0.6])、具有中学教育程度者(AOR:0.9 [95% CI 0.8-0.9])和具有高等教育程度者(AOR:0.7 [95% CI 0.6-0.9])、来自农村非正式地区者(AOR:0.8 [0.7-0.9])和农村正式地区者(AOR:0.8 [0.7-0.9])以及自评健康状况为优秀/良好者(AOR:0.4 [0.4-0.5])出现心理困扰的可能性显著更低。
研究结果强调了针对 PLHIV 设计有针对性的心理困扰干预措施的重要性,尤其是针对老年人、女性、无教育或低教育程度者以及居住在非正式城市地区者。