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作为世界绵羊基因库景观一部分的英国绵羊品种:探究基因组学应用

British Sheep Breeds as a Part of World Sheep Gene Pool Landscape: Looking into Genomic Applications.

作者信息

Romanov Michael N, Zinovieva Natalia A, Griffin Darren K

机构信息

School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.

L.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitsy Estate, Podolsk District, Moscow Region, 142132 Podolsk, Russia.

出版信息

Animals (Basel). 2021 Apr 1;11(4):994. doi: 10.3390/ani11040994.

Abstract

Sheep farming has been an important sector of the UK's economy and rural life for many centuries. It is the favored source of wool, meat and milk products. In the era of exponential progress in genomic technologies, we can now address the questions of what is special about UK sheep breed genotypes and how they differ genetically form one another and from other countries. We can reflect how their natural history has been determined at the level of their genetic code and what traces have been left in their genomes because of selection for phenotypic traits. These include adaptability to certain environmental conditions and management, as well as resistance to disease. Application of these advancements in genetics and genomics to study sheep breeds of British domestic selection has begun and will continue in order to facilitate conservation solutions and production improvement.

摘要

几个世纪以来,养羊业一直是英国经济和乡村生活的重要组成部分。它是羊毛、肉类和奶制品的首选来源。在基因组技术呈指数级发展的时代,我们现在可以解决以下问题:英国绵羊品种基因型有何特别之处,它们在基因上彼此之间以及与其他国家的绵羊品种有何不同。我们可以思考它们的自然历史是如何在遗传密码层面被决定的,以及由于对表型性状的选择,在它们的基因组中留下了哪些痕迹。这些包括对特定环境条件和管理方式的适应性,以及对疾病的抵抗力。遗传学和基因组学的这些进展已开始应用于研究英国国内选育的绵羊品种,并将继续应用,以推动保护措施和生产改进。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bd3/8103502/9909ece1b1ce/animals-11-00994-g001.jpg

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