Institute of Measurement and Sensor Technology, UMIT-Private University for Health Sciences, Medical Informatics and Technology, 6060 Hall in Tirol, Austria.
Division of Phoniatrics and Pediatric Audiology, Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital Erlangen Medical School, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Sensors (Basel). 2021 Apr 21;21(9):2923. doi: 10.3390/s21092923.
The voice producing process is a complex interplay between glottal pressure, vocal folds, their elasticity and tension. The material properties of vocal folds are still insufficiently studied, because the determination of material properties in soft tissues is often difficult and connected to extensive experimental setups. To shed light on this less researched area, in this work, a dynamic pipette aspiration technique is utilized to measure the elasticity in a frequency range of 100-1000 Hz. The complex elasticity could be assessed with the phase shift between exciting pressure and tissue movement. The dynamic pipette aspiration setup has been miniaturized with regard to a future in-vivo application. The techniques were applied on 3 different porcine larynges 4 h and 1 d postmortem, in order to investigate the deterioration of the tissue over time and analyze correlation in elasticity values between vocal fold pairs. It was found that vocal fold pairs do have different absolute elasticity values but similar trends. This leads to the assumption that those trends are more important for phonation than having same absolute values.
发声过程是声门压力、声带及其弹性和张力之间复杂的相互作用。声带的材料特性仍未得到充分研究，因为软组织中材料特性的确定通常很困难，并且与广泛的实验设置有关。为了阐明这个研究较少的领域，在这项工作中，利用动态微管抽吸技术在 100-1000 Hz 的频率范围内测量弹性。可以通过激励压力和组织运动之间的相移来评估复杂的弹性。为了未来的体内应用，已经对动态微管抽吸装置进行了小型化。该技术应用于 3 个不同的猪喉 4 小时和 1 天后，以研究组织随时间的恶化，并分析声带对之间弹性值的相关性。结果发现，声带对确实具有不同的绝对弹性值，但具有相似的趋势。这导致了这样的假设，即这些趋势对于发声比具有相同的绝对值更为重要。
