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回忆起的父母养育方式与催产素受体基因多态性相互作用,调节成人关系中的焦虑和回避行为。

Recalled Parental Bonding Interacts with Oxytocin Receptor Gene Polymorphism in Modulating Anxiety and Avoidance in Adult Relationships.

作者信息

Cataldo Ilaria, Bonassi Andrea, Lepri Bruno, Foo Jia Nee, Setoh Peipei, Esposito Gianluca

机构信息

Department of Psychology and Cognitive Science, University of Trento, 38068 Rovereto, Italy.

Mobile and Social Computing Lab, Bruno Kessler Foundation, 38123 Trento, Italy.

出版信息

Brain Sci. 2021 Apr 14;11(4):496. doi: 10.3390/brainsci11040496.

DOI:10.3390/brainsci11040496
PMID:33919740
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8070703/
Abstract

Early interactions with significant individuals affect social experience throughout the course of a lifetime, as a repeated and prolonged perception of different levels of care, independence, or control influences the modulation of emotional regulatory processes. As many factors play a role in shaping the expectations and features of social interaction, in this study, we considered the influence of parental bonding and genetic allelic variation of oxytocin receptor gene polymorphism (rs53576) over levels of experienced anxiety and avoidance in 313 young adults belonging to two different cultural contexts, namely Italy and Singapore. Results highlighted a major effect of maternal characteristics, care, and overprotection, with differences between the two cultural groups. Additionally, the interaction between rs53576 and maternal overprotection suggested different environmental susceptibility in the Italian sample and the Singaporean one. Implications for clinical work and future steps are described in the Conclusion.

摘要

早期与重要个体的互动会影响一生的社会经历,因为对不同程度的关爱、独立性或掌控力的反复且长期的感知会影响情绪调节过程的调节。由于许多因素在塑造社会互动的期望和特征方面发挥作用,在本研究中,我们考察了亲子关系以及催产素受体基因多态性(rs53576)的基因等位变异对来自意大利和新加坡这两种不同文化背景的313名年轻人的焦虑和回避体验水平的影响。结果突出了母亲的特征、关爱和过度保护的主要影响,以及两个文化群体之间的差异。此外,rs53576与母亲过度保护之间的相互作用表明,意大利样本和新加坡样本存在不同的环境易感性。结论部分描述了对临床工作的启示和未来的研究方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06eb/8070703/7f6548527c49/brainsci-11-00496-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06eb/8070703/d11245e4e424/brainsci-11-00496-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06eb/8070703/ce745f3b0818/brainsci-11-00496-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06eb/8070703/7f6548527c49/brainsci-11-00496-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06eb/8070703/d11245e4e424/brainsci-11-00496-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06eb/8070703/ce745f3b0818/brainsci-11-00496-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06eb/8070703/7f6548527c49/brainsci-11-00496-g003.jpg

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