National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
State Key Laboratory of Resources and Environmental Information System, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China.
Nutrients. 2021 Apr 14;13(4):1293. doi: 10.3390/nu13041293.
Infantile anaemia has been a severe public health problem in China for decades. However, it is unclear whether there are regional differences in the prevalence of anaemia. In this study, we used data from the China Nutrition and Health Surveillance (CNHS) to assess the prevalence of anaemia and the risk factors associated with its prevalence in different regions. We included 9596 infants aged 0-23 months from the CNHS 2013 database. An infant was diagnosed with anaemia if he/she had a haemoglobin concentration of <110 g/L. We used multivariate logistic regression to investigate the potential risk factors associated with the development of anaemia. We found that anaemia was present in 2126 (22.15%) of the infants assessed. Approximately 95% of these cases were classified as mild anaemia. Based on the guidelines laid out by the World Health Organization, 5.5% and 43.6% of the surveillance sites were categorized as having severe and moderate epidemic levels of anaemia, respectively. The prevalence of infantile anaemia in Eastern, Central and Western China was 16.67%, 22.25% and 27.44%, respectively. Premature birth, low birth weight, breastfeeding and residence in Western China were significantly associated with higher odds of developing anaemia. Female sex and having mothers with high levels of education and maternal birth age >25 years were associated with lower odds of developing anaemia. In conclusion, we observed significant regional disparities in the prevalence of infantile anaemia in China. Western China had the highest prevalence of infantile anaemia, and rural regions showed a higher prevalence of anaemia than urban regions.
婴幼儿贫血在中国已经是一个严峻的公共卫生问题,数十年来一直如此。然而,贫血的患病率是否存在地区差异尚不清楚。在这项研究中,我们使用了中国营养与健康监测(CNHS)的数据来评估不同地区贫血的患病率和与贫血患病率相关的危险因素。我们纳入了来自 CNHS2013 数据库的 9596 名 0-23 月龄的婴幼儿。如果婴幼儿的血红蛋白浓度<110g/L,则诊断为贫血。我们使用多变量 logistic 回归来调查与贫血发生相关的潜在危险因素。我们发现,2126 名(22.15%)婴幼儿患有贫血。大约 95%的贫血病例被归类为轻度贫血。根据世界卫生组织制定的指南,5.5%和 43.6%的监测点分别被归类为贫血的严重和中度流行水平。东部、中部和西部地区婴幼儿贫血的患病率分别为 16.67%、22.25%和 27.44%。早产、低出生体重、母乳喂养和居住在西部地区与发生贫血的风险更高显著相关。女性、母亲受教育程度较高和母亲生育年龄>25 岁与发生贫血的风险较低相关。总之,我们观察到中国婴幼儿贫血的患病率存在显著的地区差异。西部地区婴幼儿贫血的患病率最高,农村地区的贫血患病率高于城市地区。