García-Sánchez Susana, Gala Michal, Žoldák Gabriel
Center for Interdisciplinary Biosciences, Technology, and Innovation Park P.J. Šafárik University, Trieda SNP 1, 040 11 Košice, Slovakia.
Department of Biophysics, Faculty of Science, P. J. Šafárik University, Jesenna 5, 040 01 Košice, Slovakia.
Plants (Basel). 2021 Apr 12;10(4):751. doi: 10.3390/plants10040751.
Transcriptomics studies are available to evaluate the potential toxicity of nanomaterials in plants, and many highlight their effect on stress-responsive genes. However, a comparative analysis of overall expression changes suggests a low impact on the transcriptome. Environmental challenges like pathogens, saline, or drought stress induce stronger transcriptional responses than nanoparticles. Clearly, plants did not have the chance to evolve specific gene regulation in response to novel nanomaterials; but they use common regulatory circuits with other stress responses. A shared effect with abiotic stress is the inhibition of genes for root development and pathogen response. Other works are reviewed here, which also converge on these results.
转录组学研究可用于评估纳米材料对植物的潜在毒性，许多研究突出了它们对胁迫响应基因的影响。然而，对整体表达变化的比较分析表明，纳米材料对转录组的影响较小。与病原体、盐碱或干旱胁迫等环境挑战相比，纳米颗粒引发的转录反应较弱。显然，植物没有机会进化出针对新型纳米材料的特定基因调控机制；但它们利用与其他胁迫反应相同的调控途径。纳米材料与非生物胁迫的一个共同影响是抑制根系发育和病原体反应相关的基因。本文对其他相关研究进行了综述，这些研究也得出了相同的结果。
