CHA Bundang Medical Center, Department of Otorhinolaryngology-Head & Neck Surgery, CHA University, Seongnam 13496, Korea.
Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea.
Int J Environ Res Public Health. 2021 Apr 24;18(9):4536. doi: 10.3390/ijerph18094536.
This study explored the relation between Ménière's disease and chronic obstructive pulmonary disease (COPD). The ≥40-year-old population of the Korean National Health Insurance Service-Health Screening Cohort was included. In total, 7734 Ménière's disease patients and 30,936 control participants were enrolled. Control participants were matched for age, sex, income, and region of residence with Ménière's disease participants. The odds of having Ménière's disease given a history of COPD were analyzed using conditional logistic regression. Subgroup analyses were conducted according to age, sex, income, and region of residence. The odds of having Ménière's disease were found to be 1.18-fold higher with a history of COPD than with no history of COPD (95% confidence intervals (CI) = 1.06-1.32, E-value (CI) = 1.64 (1.31)). The ≥60 years old, male, low-income, and rural subgroups showed increased odds of developing Ménière's disease when a history of COPD was reported. A history of COPD was associated with an increased risk of Ménière's disease in the adult population.
本研究探讨了梅尼埃病与慢性阻塞性肺疾病（COPD）之间的关系。纳入了韩国国家健康保险服务-健康筛查队列中≥40 岁的人群。共纳入了 7734 例梅尼埃病患者和 30936 例对照参与者。对照参与者与梅尼埃病患者按年龄、性别、收入和居住地区进行匹配。使用条件逻辑回归分析了有 COPD 病史的患者发生梅尼埃病的几率。根据年龄、性别、收入和居住地区进行了亚组分析。结果发现，有 COPD 病史的患者发生梅尼埃病的几率是无 COPD 病史的患者的 1.18 倍（95%置信区间[CI]：1.06-1.32，E 值[CI]：1.64（1.31））。≥60 岁、男性、低收入和农村亚组中，有 COPD 病史的患者发生梅尼埃病的几率增加。COPD 病史与成年人群中梅尼埃病的发病风险增加有关。
