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评估 2015 年中国成年人慢性病与营养监测(CACDNS)中孕妇的血清锌状况。

Evaluation of Serum Zinc Status of Pregnant Women in the China Adult Chronic Disease and Nutrition Surveillance (CACDNS) 2015.

机构信息

Key Laboratory of Trace Element Nutrition of National Health Commission, National Institute of Nutrition and Health of Chinese Center for Disease Control and Prevention, Beijing 100050, China.

出版信息

Nutrients. 2021 Apr 20;13(4):1375. doi: 10.3390/nu13041375.

Abstract

The purpose of this study was to evaluate serum zinc status of pregnant women in the China Adult Chronic Disease and Nutrition Surveillance (CACDNS) in 2015-2016. A total of 7147 apparently healthy pregnant women were randomly selected in 302 national monitoring sites. Information on age, race, residence region, education, pregnancy, and family income per annum was collected, and the concentration of serum zinc was determined. The evaluation of serum zinc status was further performed according to the recommendations by the International Zinc Nutrition Consultative Group (IZiNCG). The median concentration of serum zinc was 858.9 μg/L with an interquartile range (IQR) of 712.9 μg/L and 1048.9 μg/L, while the overall prevalence of zinc deficiency was 3.5% with a 95% confidence interval (CI) of 3.0% and 3.9%. Serum zinc status of pregnant women changed greatly in the different categories, particular in pregnancy and family income per annum ( < 0.05), but no significant difference was observed in the prevalence of zinc deficiency ( > 0.05). The lower prevalence of zinc deficiency generally indicated a better zinc status for pregnant women in the CACDNS in 2015-2016. However, a well-designed evaluation system of zinc status for pregnant women should be continually optimized and improved by inducing more parameters such as biochemical, dietary, or functional indicators.

摘要

本研究旨在评估 2015-2016 年中国成人慢性病与营养监测(CACDNS)中孕妇的血清锌状况。在 302 个国家级监测点中随机选择了 7147 名显然健康的孕妇。收集了年龄、种族、居住地区、教育程度、妊娠和家庭年收入等信息,并测定了血清锌浓度。根据国际锌营养咨询组(IZiNCG)的建议进一步评估血清锌状况。血清锌浓度的中位数为 858.9μg/L,四分位间距(IQR)为 712.9μg/L 和 1048.9μg/L,而锌缺乏的总体患病率为 3.5%,95%置信区间(CI)为 3.0%至 3.9%。不同类别中孕妇的血清锌状况变化较大,特别是在妊娠和家庭年收入方面(<0.05),但锌缺乏的患病率无显著差异(>0.05)。较低的锌缺乏患病率通常表明 2015-2016 年 CACDNS 中孕妇的锌状况较好。然而,应通过引入更多生化、饮食或功能指标等参数,不断优化和改进针对孕妇的锌状况评估系统。

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