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胸腰椎爆裂骨折后路手术固定后植入物取出与保留的比较:一项系统评价和荟萃分析

Implant Removal Versus Implant Retention Following Posterior Surgical Stabilization of Thoracolumbar Burst Fractures: A Systematic Review and Meta-Analysis.

作者信息

Kweh Barry Ting Sheen, Tan Terence, Lee Hui Qing, Hunn Martin, Liew Susan, Tee Jin Wee

机构信息

5390National Trauma Research Institute, Melbourne, Victoria, Australia.

Department of Neurosurgery, Royal Melbourne Hospital, Parkville, Victoria, Melbourne.

出版信息

Global Spine J. 2022 May;12(4):700-718. doi: 10.1177/21925682211005411. Epub 2021 Apr 29.

Abstract

STUDY DESIGN

Systematic review and meta-analysis.

OBJECTIVES

To compare biomechanical and functional outcomes between implant removal and implant retention following posterior surgical fixation of thoracolumbar burst fractures.

METHODS

A search of the MEDLINE, EMBASE, Google Scholar and Cochrane Databases was conducted in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines.

RESULTS

Of the 751 articles initially retrieved, 13 published articles pooling 673 patients were included. Meta-analysis revealed there was a statistically significant improvement in sagittal Cobb Angle by 16.48 degrees (9.13-23.83, p < 0.01) after surgical stabilization of thoracolumbar burst fractures. This correction decremented to 9.68 degrees (2.02-17.35, p < 0.01) but remained significant at the time of implant removal approximately 12 months later. At final follow-up, the implant removal group demonstrated a 10.13 degree loss (3.00-23.26, p = 0.13) of reduction, while the implant retention group experienced a 10.17 degree loss (1.79-22.12, p = 0.10). There was no statistically significant difference in correction loss between implant retention and removal cohorts (p = 0.97). Pooled VAS scores improved by a mean of 3.32 points (0.18 to 6.45, p = 0.04) in the combined removal group, but by only 2.50 points (-1.81 to 6.81, p = 0.26) in the retention group. Oswestry Disability Index scores also improved after implant removal by 7.80 points (2.95-12.64, p < 0.01) at 1 year and 11.10 points (5.24-16.96, p < 0.01) at final follow-up.

CONCLUSIONS

In younger patients with thoracolumbar burst fractures who undergo posterior surgical stabilization, planned implant removal results in superior functional outcomes without significant difference in kyphotic angle correction loss compared to implant retention.

摘要

研究设计

系统评价与荟萃分析。

目的

比较胸腰椎爆裂骨折后路手术固定后取出内固定物与保留内固定物的生物力学和功能结果。

方法

按照系统评价和荟萃分析的首选报告项目(PRISMA)指南,对MEDLINE、EMBASE、谷歌学术和考克兰数据库进行检索。

结果

最初检索到751篇文章,纳入13篇发表文章,共673例患者。荟萃分析显示,胸腰椎爆裂骨折手术稳定后矢状面Cobb角有统计学意义的改善,改善了16.48度(9.13 - 23.83,p < 0.01)。大约12个月后取出内固定物时,这种矫正减少到9.68度(2.02 - 17.35,p < 0.01),但仍具有统计学意义。在末次随访时,取出内固定物组的矫正丢失为10.13度(3.00 - 23.26,p = 0.13),而保留内固定物组的矫正丢失为10.17度(1.79 - 22.12,p = 0.10)。保留和取出内固定物队列之间的矫正丢失无统计学显著差异(p = 0.97)。联合取出组的VAS评分平均改善3.32分(0.18至6.45,p = 0.04),而保留组仅改善2.50分(-1.81至6.81,p = 0.26)。取出内固定物后,奥斯威斯功能障碍指数评分在1年时改善7.80分(2.95 - 12.64,p < 0.01),在末次随访时改善11.10分(5.24 - 16.96,p < 0.01)。

结论

在接受后路手术稳定的年轻胸腰椎爆裂骨折患者中,与保留内固定物相比,计划取出内固定物可带来更好的功能结果,且后凸角矫正丢失无显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5763/9109574/b71546119326/10.1177_21925682211005411-fig1.jpg

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