Ocular Oncology Service, Department of Ophthalmology, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Suite 5415, Cincinnati, OH 45267-0567, USA.
Medicine, 231 Albert Sabin Way, Suite 5412, Cincinnati, OH 45267-0567, USA. Electronic address: https://twitter.com/mauradinicola.
Med Clin North Am. 2021 May;105(3):531-550. doi: 10.1016/j.mcna.2021.02.005. Epub 2021 Apr 2.
Several neoplastic processes can involve the eye, either primarily or secondary to a systemic malignancy. The most common primary tumors of the eye include conjunctival and uveal melanoma, retinoblastoma, conjunctival and intraocular lymphoma, and ocular surface squamous neoplasia. Metastatic spread from systemic malignancies, especially of the breast and lung, also can involve the eye. A combination of ophthalmologic examination, ancillary testing, and cytologic/histopathologic evaluation leads to accurate diagnosis. Management consists of surgery, radiotherapy, chemotherapy, and immunotherapy delivered in various forms.
多种肿瘤过程可累及眼睛，无论是原发于眼部还是全身恶性肿瘤转移至眼部。最常见的眼部原发性肿瘤包括结膜和葡萄膜黑色素瘤、视网膜母细胞瘤、结膜和眼内淋巴瘤，以及眼表面鳞状细胞肿瘤。全身恶性肿瘤（尤其是乳腺癌和肺癌）转移也可累及眼睛。眼科检查、辅助检查以及细胞学/组织病理学评估相结合可得出准确的诊断。治疗包括手术、放疗、化疗和免疫治疗，采用的形式各异。
