Lv Jing, Gao Jing, Wu Bo, Yao Meiling, Yang Yudong, Chai Tongjie, Li Ning
Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Sino-German Cooperative Research Center for Zoonosis of Animal Origin Shandong Province, Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Taian, China.
Center for Disease Control and Prevention, Taian, China.
Front Vet Sci. 2021 Apr 13;8:572012. doi: 10.3389/fvets.2021.572012. eCollection 2021.
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused great harm to global public health, resulting in a large number of infections among the population. However, the epidemiology of coronavirus has not been fully understood, especially the mechanism of aerosol transmission. Many respiratory viruses can spread via contact and droplet transmission, but increasing epidemiological data have shown that viral aerosol is an essential transmission route of coronavirus and influenza virus due to its ability to spread rapidly and high infectiousness. Aerosols have the characteristics of small particle size, long-time suspension and long-distance transmission, and easy access to the deep respiratory tract, leading to a high infection risk and posing a great threat to public health. In this review, the characteristics of viral aerosol generation, transmission, and infection as well as the current advances in the aerosol transmission of zoonotic coronavirus and influenza virus are summarized. The aim of the review is to strengthen the understanding of viral aerosol transmission and provide a scientific basis for the prevention and control of these diseases.
由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的2019冠状病毒病(COVID-19)对全球公共卫生造成了巨大危害,导致大量人群感染。然而,冠状病毒的流行病学尚未完全了解,尤其是气溶胶传播机制。许多呼吸道病毒可通过接触和飞沫传播,但越来越多的流行病学数据表明,病毒气溶胶因其传播迅速和高传染性,是冠状病毒和流感病毒的重要传播途径。气溶胶具有粒径小、悬浮时间长、传播距离远、易进入下呼吸道等特点,导致感染风险高,对公共卫生构成重大威胁。本文综述了病毒气溶胶产生、传播和感染的特点,以及人畜共患冠状病毒和流感病毒气溶胶传播的研究进展。综述的目的是加强对病毒气溶胶传播的认识,为这些疾病的防控提供科学依据。