Universidad Autónoma de Nuevo León, FIME. Av. Universidad S/N, Ciudad Universitaria, 66451, San Nicolás de los Garza, NL, Mexico.
Universidad Autónoma de Nuevo León, CICFM-FCFM. Av. Universidad S/N, Ciudad Universitaria, 66451, San Nicolás de los Garza, NL, Mexico.
J Mech Behav Biomed Mater. 2021 Aug;120:104554. doi: 10.1016/j.jmbbm.2021.104554. Epub 2021 Apr 24.
This article focuses on obtaining ultra high molecular weight polyethylene (UHMWPE) material reinforced with functionalized single-walled carbon nanotubes (f-SWCNTs) and the manufacturing of unicompartmental knee implants via Single-Point Incremental Forming process (SPIF). The physicochemical properties of the developed UHMWPE reinforced with 0.01 and 0.1 wt% concentrations of f-SWCNTs are investigated using Raman and Thermogravimetic Analysis (TGA). Tensile mechanical tests performed in the nanocomposite material samples reveal a 12% improvement in their Young's modulus when compare to that of the pure UHMWPE material samples. Furthermore, the surface biocompatibility of the UHMWPE reinforced with f-SWCNTs materials samples was evaluated with human osteoblast cells. Results show cell viability enhancement with good cell growth and differentiation after 14 incubation days, that validates the usefulness of the developed nanocomposite material in the production of hip and knee artificial implants, and other biomedical applications.
本文主要研究了通过单点增量成形工艺(SPIF)获得功能化单壁碳纳米管(f-SWCNT)增强超高分子量聚乙烯(UHMWPE)材料,并制造单室膝关节植入物。采用拉曼和热重分析(TGA)研究了开发的 0.01 和 0.1wt%浓度 f-SWCNT 增强 UHMWPE 的物理化学性质。对纳米复合材料样品进行的拉伸力学测试表明,与纯 UHMWPE 材料样品相比,其杨氏模量提高了 12%。此外,还用人骨肉瘤细胞评估了 f-SWCNT 增强 UHMWPE 材料样品的表面生物相容性。结果表明,在 14 天的孵育后,细胞活力增强,细胞生长和分化良好,这验证了所开发的纳米复合材料在髋关节和膝关节人工植入物以及其他生物医学应用中的有用性。