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利用真实世界数据估计 2014 年至 2019 年期间中国厦门 2 型糖尿病患病率和发病率的变化趋势。

Using real-world data to estimate the changing trends in the prevalence and incidence of type 2 diabetes mellitus in Xiamen of China from 2014 to 2019.

机构信息

School of Medicine, Xiamen University, Xiamen, 361003, China.

Xiamen Diabetes Institute, The First Affiliated Hospital of Xiamen University, Xiamen, 361003, China.

出版信息

BMC Endocr Disord. 2021 May 1;21(1):92. doi: 10.1186/s12902-021-00759-w.

DOI:10.1186/s12902-021-00759-w
PMID:33933044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8088665/
Abstract

BACKGROUND

The prevalence of diabetes is increasing worldwide. Our study aimed to estimate the changing trends in the prevalence and incidence of diagnosed type 2 diabetes mellitus (T2DM) among Xiamen residents and the floating population using real-world data.

METHOD

We used real-world data from the System of Xiamen Citizens Health Information from 2014 to 2019 to estimate the changing trends in the prevalence and incidence of diagnosed T2DM. The System included the diagnosis of diabetes and the prescription of hypoglycemic drugs. Prevalent cases of T2DM were individuals who were diagnosed with T2DM and/or using hypoglycemic drugs. Incident cases were individuals with diagnosed T2DM and/or using hypoglycemic drugs in 2014 or 2019 who had not been diagnosed and/or did not use hypoglycemic drugs in the past.

RESULTS

In 2014 and 2019, the prevalence of T2DM in Xiamen was 4.04 and 4.84%, respectively. In 2014 and 2019, the incidence rate of T2DM in Xiamen was 14.1 per 1000 person-year and 15.0 per 1000 person-year, respectively. There was a significant increase in both the prevalence (Prevalence difference: 0.80, 95%CI 0.76-0.83%, P < 0.001) and the incidence of T2DM (Incidence difference: 0.9, 95%CI 0.7-1.1, P < 0.001). in Xiamen. The prevalence and incidence of T2DM in people aged 18-39 increased significantly (P < 0.001), while the prevalence and incidence of T2DM in people aged 40-69 reduced significantly (P < 0.001).

CONCLUSIONS

There was a significant increase in the prevalence and incidence of T2DM in Xiamen from 2014 to 2019 especially among those with younger age.

摘要

背景

糖尿病的患病率在全球范围内呈上升趋势。本研究旨在使用真实世界数据估计厦门居民和流动人口中诊断为 2 型糖尿病(T2DM)的患病率和发病率的变化趋势。

方法

我们使用 2014 年至 2019 年厦门市居民健康信息系统的真实世界数据来估计诊断为 2 型糖尿病的患病率和发病率的变化趋势。该系统包括糖尿病的诊断和降血糖药物的处方。T2DM 的现患病例是指被诊断患有 T2DM 和/或使用降血糖药物的个体。新发病例是指 2014 年或 2019 年被诊断患有 T2DM 和/或使用降血糖药物且在过去未被诊断和/或未使用降血糖药物的个体。

结果

2014 年和 2019 年,厦门市 T2DM 的患病率分别为 4.04%和 4.84%。2014 年和 2019 年,厦门市 T2DM 的发病率分别为 14.1/1000 人年和 15.0/1000 人年。T2DM 的患病率(患病率差异:0.80,95%CI 0.76-0.83%,P<0.001)和发病率(发病率差异:0.9,95%CI 0.7-1.1,P<0.001)均有显著增加。18-39 岁人群 T2DM 的患病率和发病率显著增加(P<0.001),而 40-69 岁人群 T2DM 的患病率和发病率显著降低(P<0.001)。

结论

2014 年至 2019 年,厦门市 T2DM 的患病率和发病率显著增加,尤其是在年轻人群中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26da/8088665/1ad7dc6da358/12902_2021_759_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26da/8088665/42c462d53f4e/12902_2021_759_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26da/8088665/1ad7dc6da358/12902_2021_759_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26da/8088665/42c462d53f4e/12902_2021_759_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26da/8088665/1ad7dc6da358/12902_2021_759_Fig2_HTML.jpg

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