Choi Won-Young
Division of Interdisciplinary Industrial Studies, Hanyang University, Seoul, Republic of Korea.
Disaster Med Public Health Prep. 2021 May 3:1-6. doi: 10.1017/dmp.2021.139.
The aim of this study was to evaluate the mortality rates of 566,602 patients with coronavirus disease (COVID-19) based on sex, age, and the presence or absence of underlying diseases and determine whether the underlying disease provides prognostic information specifically related to death.
The mortality rate was evaluated using conditional probability to identify the significant factors, and adjusted odds ratios (ORs) using a multivariable logistic regression analysis were estimated.
The mortality rate of patients with underlying health conditions was 12%, which was 4 times higher than that of patients without underlying health conditions. Furthermore, the mortality rates of women and men with underlying health conditions were 5.5 and 3.4 times higher than the mortality rates of patients without underlying health conditions, respectively. In a multivariable logistic regression analysis including sex, age, and underlying health conditions, male sex (OR: 1.83), age ≥ 41 y (ORs > 2.70), and underlying health conditions (OR: 2.20) were confirmed as risk factors for death.
More attention should be paid to older patients with underlying diseases and male patients with underlying diseases as the probability of death in this population was significantly higher.
本研究旨在基于性别、年龄以及是否存在基础疾病评估566,602例冠状病毒病(COVID-19)患者的死亡率,并确定基础疾病是否提供与死亡特别相关的预后信息。
使用条件概率评估死亡率以识别显著因素,并通过多变量逻辑回归分析估计调整后的比值比(OR)。
有基础健康状况的患者死亡率为12%,是无基础健康状况患者的4倍。此外,有基础健康状况的女性和男性死亡率分别比无基础健康状况患者的死亡率高5.5倍和3.4倍。在包括性别、年龄和基础健康状况的多变量逻辑回归分析中,男性(OR:1.83)、年龄≥41岁(OR>2.70)和基础健康状况(OR:2.20)被确认为死亡的危险因素。
应更加关注有基础疾病的老年患者和有基础疾病的男性患者,因为该人群的死亡概率显著更高。