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光动力疗法在免疫相关性疾病中的应用。

Application of photodynamic therapy in immune-related diseases.

机构信息

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, No. 14, Section 3, Renminnan Road, Chengdu, Sichuan 610041, China.

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, No. 14, Section 3, Renminnan Road, Chengdu, Sichuan 610041, China.

出版信息

Photodiagnosis Photodyn Ther. 2021 Jun;34:102318. doi: 10.1016/j.pdpdt.2021.102318. Epub 2021 Apr 30.

Abstract

Photodynamic therapy (PDT) is a therapeutic modality that utilizes photodamage caused by photosensitizers and oxygen after exposure to a specific wavelength of light. Owing to its low toxicity, high selectivity, and minimally invasive properties, PDT has been widely applied to treat various malignant tumors, premalignant lesions, and infectious diseases. Moreover, there is growing evidence of its immunomodulatory effects and potential for the treatment of immune-related diseases. This review mainly focuses on the effect of PDT on immunity and its application in immune-related diseases.

摘要

光动力疗法(PDT)是一种利用光敏剂和氧气在特定波长光照射下产生的光损伤来进行治疗的方法。由于其低毒性、高选择性和微创性,PDT 已广泛应用于治疗各种恶性肿瘤、癌前病变和传染病。此外,越来越多的证据表明其具有免疫调节作用和治疗免疫相关疾病的潜力。本综述主要关注 PDT 对免疫的影响及其在免疫相关疾病中的应用。

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